轉(zhuǎn)錄輔助因子退變樣蛋白2抗體 返回列表頁

轉(zhuǎn)錄輔助因子退變樣蛋白2抗體

英文名稱 VGLL2
中文名稱 轉(zhuǎn)錄輔助因子退變樣蛋白2抗體
別    名 Protein VITO1; Transcription cofactor vestigial like 2; Transcription cofactor vestigial like protein 2; Transcription cofactor vestigial-like protein 2; Vestigial like 2; Vestigial like 2 (Drosophila); Vgl-2; VGL2; VGLL 2; Vgll2; VGLL2_HUMAN; VITO1.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  干細胞  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human VGLL2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Vgl-2, also known as VITO-1, is a 317 amino acid protein that contains a domain through which it interacts with TEF-1, a protein that plays a role in controlling the expression of numerous genes. Specific to skeletal muscle, Vgl-2 is expressed highly in adult fast muscle and is expressed at lower levels in adult slow muscle and fetal skeletal muscle. During muscle differentiation, Vgl-2 mRNA levels increase and Vgl-2 translocates from the cytoplasm to the nucleus. Overexpression of Vgl-2 in MYOD-transfected 10T1/2 mouse embryonic fibroblasts increases expression of myosin heavy chain (MHC), which is a marker of terminal muscle differentiation. This evidence suggests that Vgl-2 is essential for muscle gene expression. There are two isoforms of Vgl-2 that are produced as a result of alternative splicing events. 

Function:
May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles. 

Subunit:
Interacts with TEFs. Binds to TEAD1/TEF1. 

Subcellular Location:
Nucleus.xy-9164R    TRIM7糖原生成素相互作用蛋白抗體
xy-9165R    RNF89環(huán)指蛋白89
xy-6196R    TGM2 谷氨酰胺轉(zhuǎn)胺酶2抗體
xy-6197R    TIM4T淋巴細胞膜蛋白4抗體
xy-5415R    phospho-Tau protein(Ser721)磷酸化微管相關(guān)蛋白抗體
xy-5416R    phospho-Tau protein(Ser214)磷酸化微管相關(guān)蛋白抗體
xy-5417R    phospho-Tau protein(Ser199)磷酸化微管相關(guān)蛋白抗體
xy-4221R    TM7SF2脫氫膽固醇還原酶14抗體
xy-6190R    Thyroxine Binding Globulin甲狀腺素結(jié)合球蛋白抗體
xy-4219R    TBL1X轉(zhuǎn)導(dǎo)素β1X連鎖蛋白抗體
xy-4198R    Endothelin B Receptor內(nèi)皮素B受體抗體
xy-4220R    TBLR1轉(zhuǎn)導(dǎo)素β1X連鎖受體蛋白1抗體
xy-4223R    TRAP220甲狀腺受體相關(guān)蛋白220抗體
xy-5700R    phospho-TRAP220(Thr1457) 磷酸化甲狀腺受體相關(guān)蛋白220抗體
xy-6116R    TUSC5抑癌基因5抗體
xy-6117R    Tomoregulin-1腦腫瘤抑癌蛋白1抗體
xy-6114R    TUSC1肺癌抑癌蛋白1抗體
xy-6115R    TUSC3前列腺癌抑癌蛋白3抗體
xy-6221R    THRA1甲狀腺激素受體α1抗體
xy-6222R    THRA1+2甲狀腺激素受體α1+α2抗體
xy-2914R    TIP47脂滴相關(guān)蛋白TIP47抗體
xy-6502R    Testin腫瘤抑制基因Testin抗體
xy-6300R    TEM7R腫瘤血管內(nèi)皮標(biāo)記相關(guān)蛋白質(zhì)7抗體
xy-6220R    TRIM31環(huán)指蛋白HCG1抗體
xy-11489R    TNRC6B三核苷酸重復(fù)蛋白6B抗體
xy-11490R    Torsin A扭轉(zhuǎn)蛋白A抗體
xy-10106R    phospho-Tau protein (Thr548)磷酸化微管相關(guān)蛋白抗體
xy-10107R    phospho-Tau protein(Ser739)磷酸化微管相關(guān)蛋白抗體
xy-10108R    phospho-Tau protein (Ser579)磷酸化微管相關(guān)蛋白抗體
xy-10109R    phospho-Tau protein(Ser531)磷酸化微管相關(guān)蛋白抗體
xy-10110R    phospho-Tau protein(Ser516)磷酸化微管相關(guān)蛋白抗體