磷酸化鳥(niǎo)苷酸轉(zhuǎn)換因子VAV1抗體 返回列表頁(yè)

磷酸化鳥(niǎo)苷酸轉(zhuǎn)換因子VAV1抗體

英文名稱 phospho-VAV1 (Tyr160)
中文名稱 磷酸化鳥(niǎo)苷酸轉(zhuǎn)換因子VAV1抗體
別    名 VAV1(phospho Y160); Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN; VAV1.
  
說(shuō) 明 書(shū) 0.1ml  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  G蛋白偶聯(lián)受體  t-淋巴細(xì)胞  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human VAV1 around the phosphorylation site of Tyr160
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012].

Function:
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.xy-1122R    semaphorin 3F臂板蛋白3F抗體
xy-1123R    Sema4C臂板蛋白4C抗體
xy-1128R    SGLT1鈉-糖共轉(zhuǎn)運(yùn)載體1抗體
xy-0211R    SHANK 1富含脯氨酸突觸相關(guān)蛋白SHANK1抗體
xy-1175R    SHBG性激素結(jié)合球蛋白抗體
xy-1129R    SHP-1造血細(xì)胞磷酸酶抗體
xy-1233R    SHP2蛋白酪氨酸磷酸酶2抗體
xy-0496R    SLC24A5可溶性載質(zhì)轉(zhuǎn)運(yùn)蛋白SLC24A5抗體
xy-2121R    SCYLV甘蔗SCYLV抗體
xy-2536R    SREBP-2膽固醇調(diào)節(jié)元件結(jié)合蛋白2抗體
xy-2544R    SLAMF7SLAMF7抗體
xy-6733R    SECTM1分泌和跨膜蛋白1抗體
xy-6732R    SDF4基質(zhì)細(xì)胞衍生因子4抗體（鈣結(jié)合蛋白）
xy-6737R    SVH肝癌蛋白剪接變異體蛋白抗體
xy-7011R    SDCCAG8結(jié)腸癌抗原8抗體
xy-7009R    SART3T淋巴細(xì)胞識(shí)別的鱗狀細(xì)胞癌SART3抗體
xy-3427R    phospho-STAT1 (Ser727)磷酸化信號(hào)轉(zhuǎn)導(dǎo)與轉(zhuǎn)錄激活因子1抗體
xy-6731R    SDCG1血清學(xué)定義結(jié)腸癌抗原1抗體
xy-3484R    Smad3細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)分子SMAD3抗體
xy-3425R    Phospho-Smad3 (Ser423 + Ser425)磷酸化細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)分子SMAD3抗體
xy-7010R    SDCCAG10結(jié)腸癌抗原10抗體
xy-1609R    SATB1核基質(zhì)結(jié)合區(qū)結(jié)合蛋白1抗體
xy-3579R    SLC40A1細(xì)胞膜鐵轉(zhuǎn)運(yùn)蛋白FP1抗體
xy-3575R    SSEA3階段特異性胚胎表面抗原-3抗體
xy-6596R    STMN3原癌基因18家族STMN3蛋白抗體
xy-3609R    SSEA4階段特異性胚胎表面抗原4抗體
xy-2178R    SM22 Alpha細(xì)胞骨架相關(guān)蛋白抗體
xy-0457R    phospho-SMAD2(Ser425)磷酸化細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)分子SMAD2抗體
xy-3418R    Phospho-Smad1/5 (Ser463 + Ser465)磷酸化細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)分子Smad-1/5抗體
xy-3419R    Phospho-Smad2(Ser465 + Ser467)磷酸化細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)分子SMAD2抗體