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泛素激活酶2H抗體

英文名稱(chēng) Ube2H
中文名稱(chēng) 泛素激活酶2H抗體
別    名 E2 20K; Ubc H2; UBC8; UBCH 2; UBCH; UBCH2; Ube2h; UBE2H_HUMAN; Ubiquitin carrier protein H; Ubiquitin conjugating enzyme E2 H; Ubiquitin conjugating enzyme E2H (UBC8 homolog yeast); Ubiquitin conjugating enzyme E2H; Ubiquitin protein ligase H; Ubiquitin-conjugating enzyme E2 H; Ubiquitin-conjugating enzyme E2-20K; Ubiquitin-protein ligase H.

說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse, Rat, Chicken, Dog, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ube2H/UBCH2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
UBE2H, also known as UBC8, UBCH, UBCH2 or E2-20K, is a 183 amino acid protein involved in ubiquitin-mediated protein degradation. Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). One of several members of the ubiquitin-conjugating enzyme family, UBE2H functions as an E2 ubiquitin-conjugating enzyme that acts to catalyze the covalent attachment of ubiquitin residues to various proteins, including Histone H2A. UBE2H shares 100% identity with its mouse counterpart and 98% identity with its frog and zebrafish homologs, suggesting a conserved function between species. Multiple isoforms of UBE2H exist due to alternative splicing events.

Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A.xy-6071R    LRP12低密度脂蛋白受體相關(guān)蛋白12抗體（抑制腫瘤蛋白7）
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xy-2647R    LAIR-1白細(xì)胞相關(guān)免疫球蛋白樣受體1抗體
xy-2650R    Langerin/CD207白細(xì)胞分化抗原CD207抗體
xy-2655R    LTB4-R2白三烯B4受體2抗體
xy-2648R    LAIR-2白細(xì)胞相關(guān)免疫球蛋白樣受體2抗體
xy-6069R    LLGL1相似腫瘤抑制基因HUGL抗體
xy-6319R    IL-1 Beta白介素1β抗體
xy-0814R    Beta-lactoglobulinβ-乳球蛋白抗體
xy-12150R    LPPR1脂質(zhì)磷酸磷酸酶相關(guān)蛋白1/可塑性相關(guān)基因3抗體
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xy-9327R    LRCH1富含亮氨酸重復(fù)家庭蛋白1抗體
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xy-0109R    Leptin receptor(long)瘦素受體抗體（長(zhǎng)）
xy-1058R    LIF白血病抑制因子抗體
xy-1177R    Lingo-1Nogo受體反應(yīng)蛋白抗體
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xy-0409R    Leptin瘦素抗體
xy-0410R    Leptin receptor瘦素受體抗體
xy-0109M    Leptin receptor(long)瘦素受體抗體（長(zhǎng)）
xy-9708R    LCE1A晚期包膜蛋白1抗體
xy-6862R    LANPL富含亮氨酸樣酸性核蛋白抗體
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xy-9711R    LIPK脂肪酶家庭成員K抗體
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