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突觸囊泡融合蛋白Unc18-3抗體

英文名稱 Unc18-3
中文名稱 突觸囊泡融合蛋白Unc18-3抗體
別    名 Munc 18 3; Munc18 3; Munc 18-3; Protein unc-18 homolog 3; STXB3_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
產(chǎn)品應(yīng)用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 68kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Unc18-3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
xy-6679R    MAOA單氨氧化酶A抗體
xy-8512R    MSX1MSH同源蛋白1樣蛋白抗體
xy-9340R    MARCH6膜相關(guān)環(huán)指蛋白6抗體
xy-5787R    MMP19基質(zhì)金屬蛋白酶18/19
xy-5781R    MIG7富含半胱氨酸蛋白質(zhì)MIG7抗體
xy-5936R    MOS原癌基因絲氨酸/蘇氨酸蛋白激酶MOS抗體
xy-5792R    MCPIP1單核細(xì)胞趨化誘導(dǎo)蛋白1抗體
xy-5885R    Myosin heavy chain 1肌球蛋白重鏈抗體
xy-5876R    MMP-28基質(zhì)金屬蛋白酶28抗體
xy-5875R    MMP-23基質(zhì)金屬蛋白酶23抗體
xy-6551R    MimitinMYC誘導(dǎo)線粒體蛋白抗體
xy-5879R    MUC7粘蛋白7抗體
xy-5877R    MUC13粘蛋白13抗體
xy-5878R    MUC15粘蛋白15抗體
xy-5874R    MMP-22基質(zhì)金屬蛋白酶22抗體
xy-6547R    MAG1肺癌轉(zhuǎn)移相關(guān)蛋白抗體
xy-6548R    MARVELD1候選腫瘤抑制基因MARVELD1抗體
xy-6550R    MTCP1成熟T淋巴細(xì)胞增殖蛋白1抗體
xy-6255R    MAPK8IP1絲裂原活化蛋白激酶8相互作用蛋白1抗體
xy-4129R    MYL6肌球蛋白輕鏈6抗體
xy-5479R    phospho-MEF2C(Ser59)磷酸化肌細(xì)胞增強(qiáng)因子2C抗體
xy-5472R    phospho-MCAM(Tyr641)磷酸化黑色素瘤細(xì)胞粘附分子CD146抗體
xy-4130R    MEF2C肌細(xì)胞增強(qiáng)因子2C抗體
xy-3910R    MSH γ1促黑細(xì)胞激素γ1抗體
xy-0102M    PKM2小鼠抗丙酮酸激酶-M2抗體
xy-3836R    PABP (Methyl Arg455/460)甲基化多聚腺苷酸結(jié)合蛋白抗體
xy-6004R    MIG6有絲分裂原誘導(dǎo)基因6抗體
xy-2988R    Mitofusin 2線粒體融合蛋白Mfn2抗體
xy-2931R    Mammaglobin A乳腺珠蛋白1抗體
xy-2380R    MYL9肌球蛋白輕鏈9抗體
xy-4060R    phospho-MYL9(Thr19)磷酸化肌球蛋白輕鏈9抗體
Function:
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity).

Subunit:
Interacts with DOC2B; the interaction is direct, occurs at the cell membrane, excludes interaction with STX4 and regulates glucose-stimulated insulin secretion (By similarity). Interacts with STX4.

Subcellular Location:
Cytoplasm, cytosol. Cell membrane.

Tissue Specificity:
Megakaryocytes and plaets.

Similarity:
Belongs to the STXBP/unc-18/SEC1 family.