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泛素特異性蛋白酶9X抗體

英文名稱 USP9X
中文名稱 泛素特異性蛋白酶9X抗體
別    名 X chromosome; X-linked; Deubiquitinating enzyme FAF X; Deubiquitinating enzyme FAF-X; DFFRX; Fafl; Fam; Fat facets homolog; Fat facets in mammals; Fat facets protein related X linked; Fat facets protein related X-linked; Fat facets protein-related; hFAM; Probable ubiquitin carboxyl terminal hydrolase FAF X; Probable ubiquitin carboxyl-terminal hydrolase FAF-X; Ubiquitin carboxyl-terminal hydrolase FAM; Ubiquitin specific processing protease FAF X; Ubiquitin specific protease 9 X chromosome; Ubiquitin thiolesterase FAF X; Ubiquitin thiolesterase FAF-X; Ubiquitin-specific processing protease FAF-X; Ubiquitin-specific protease 9; Ubiquitin-specific protease 9 X chromosome; Ubiquitin-specific-processing protease FAF-X; USP9 (gene name); Usp9x; USP9X_HUMAN
  
說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Cow, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 292kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from hu USP9X
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Function:
Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33.

Subunit:
Interacts with SMAD4, MARK4, NUAK1 and BIRC5/survivin.xy-9544R    MMS21E3連接酶MMS21蛋白抗體
xy-11029R    MID2/RNF60/Midline-2環(huán)指蛋白60抗體
xy-9867R    MYL7肌球蛋白輕鏈7抗體
xy-9868R    MYBPC3心臟肌球蛋白結(jié)合蛋白抗體
xy-9610R    MYH9肌球蛋白重鏈9抗體
xy-8562R    MLLT11髓系/淋巴或混合型白血病11抗體
xy-8461R    MX2干擾素誘導(dǎo)GTP結(jié)合蛋白MX2抗體
xy-6454R    BA46乳腺上皮細(xì)胞抗原BA46抗體
xy-0401R    Metal ion transporter擬南介金屬離子轉(zhuǎn)運(yùn)蛋白抗體
xy-0761R    Midnolin中腦核仁蛋白抗體
xy-9862R    MYH7B肌球蛋白重鏈7抗體
xy-9863R    MYOM1肌間蛋白1抗體
xy-9864R    MYOM2肌間蛋白2抗體
xy-9865R    MYLK3肌球蛋白輕鏈激酶3抗體
xy-9866R    MYLK2肌球蛋白輕鏈激酶2抗體
xy-6781R    MAP3K10絲裂原活化蛋白激酶3K10抗體
xy-6782R    MST4絲氨酸/蘇氨酸蛋白激酶MST4抗體
xy-7761R    Myosin VIIa肌球蛋白7a/常染色體隱性耳聾蛋白2抗體
xy-8084R    MBC1膀胱癌突變蛋白1抗體
xy-9376R    MURF3肌肉特定環(huán)指蛋白3抗體
xy-9377R    EDPF1腸細(xì)胞分化相關(guān)因子1抗體
xy-9379R    RNF62環(huán)指蛋白62抗體
xy-6933R    MICBMHC I類鏈相關(guān)蛋白B
xy-7115R    MLC1膜蛋白MLC1抗體
xy-3278R    Phospho-MKP1 (Ser359)磷酸化絲裂原活化蛋白激酶磷酸酶-1抗體
xy-3279R    Phospho-MKP1 (Ser296)磷酸化絲裂原活化蛋白激酶磷酸酶-1抗體
xy-2992R    MLK3絲氨酸/蘇氨酸蛋白激酶MLK3抗體
xy-3280R    Phospho-MLK3(Thr277 + Ser281)磷酸化絲氨酸/蘇氨酸蛋白激酶MLK3抗體
xy-2995R    MSK1有絲分裂原和應(yīng)激活化型蛋白激酶1抗體
xy-3281R    Phospho-MSK1 (Ser360)磷酸化有絲分裂原和應(yīng)激活化型蛋白激酶1抗體
xy-3282R    Phospho-MSK1 (Ser212)磷酸化有絲分裂原和應(yīng)激活化型蛋白激酶1抗體
xy-3283R    Phospho-MSK1 (Ser376)磷酸化有絲分裂原和應(yīng)激活化型蛋白激酶1抗體
xy-3284R    Phospho-MSK1 (Thr581)磷酸化有絲分裂原和應(yīng)激活化型蛋白激酶1抗體