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葡萄糖神經(jīng)酰胺合成酶抗體

英文名稱(chēng) UGCG
中文名稱(chēng) 葡萄糖神經(jīng)酰胺合成酶抗體
別    名 CEGT_HUMAN; Ceramide glucosyltransferase; GCS; GLCT 1; GLCT-1; GLCT1; Glucosylceramide synthase; UDP glucose ceramide glucosyltransferase; UDP glucose N acylsphingosine D glucosyltransferase; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase; Ugcg.

說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  細(xì)胞凋亡  細(xì)胞分化  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human UGCG (31-98aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Glucosylceramide synthase (GCS), also designated ceramide glucosyltransferase, belongs to the glycosyltransferase 2 family. It is a widely expressed integral membrane protein encoded by UGCG. The enzyme can be found in the plasma membrane of all eukaryotic cells, and a significant concentration of glucosylceramide synthase activity has been reported in the Golgi complex. Glucosylceramide synthase catalyzes the first glycosylation step in glycosphingolipid biosynthesis and functions as a glucosyltransferase and flippase in the transfer of glucose to ceramide. Glucosylceramide synthase operates in cell recognition, cell proliferation and differentiation, immune recognition and signal transduction. The regulation of ceramide levels through glucosylceramide synthase has been associated with the induction of apoptosis and notable research implicates this relationship with drug-induced apoptosis in a variety of cell types.

Function:
Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".

Subcellular Location:
Golgi apparatus membrane.

Tissue Specificity:
Found in all tissues examined.xy-1194R    NFkB p105 / p50細(xì)胞核因子p50/k基因結(jié)合核因子抗體
xy-0123R    Neurokinin A Receptor神經(jīng)激肽A受體/K物質(zhì)受體抗體
xy-0070R    NKB神經(jīng)激肽B抗體
xy-1055R    Neurocan神經(jīng)粘蛋白抗體
xy-0289R    Neurofascin神經(jīng)束蛋白抗體
xy-0708R    NF-H高分子量神經(jīng)絲蛋白抗體
xy-0465R    NFKB p65細(xì)胞核因子/k基因結(jié)合核因子抗體
xy-0707R    NF-L低分子量神經(jīng)絲蛋白抗體
xy-0710R    NF-M中分子量神經(jīng)絲蛋白抗體
xy-6390R    Necdin生長(zhǎng)抑制蛋白NDN抗體
xy-0067R    NGFB神經(jīng)生長(zhǎng)因子β抗體
xy-1065R    C9orf127鼻咽癌細(xì)胞相關(guān)基因6抗體
xy-0505R    Sodium / Hydrogen Exchanger 1鈉氫通道蛋白抗體
xy-7694R    SLC12A3鈉氯離子轉(zhuǎn)運(yùn)蛋白抗體
xy-1027R    NSE神經(jīng)元特異性烯醇化酶/γ 烯醇化酶抗體
xy-0160R    Neurotrophin 3神經(jīng)營(yíng)養(yǎng)因子-3前蛋白抗體
xy-0178R    Nurr1核受體相關(guān)因子-1抗體
xy-1074R    Nrf2核因子2相關(guān)因子2抗體
xy-0693R    Neuropilin 1神經(jīng)纖毛蛋白1抗體
xy-0158R    Neurotrophin 4神經(jīng)生長(zhǎng)因子4/5抗體
xy-9717R    Nidogen 2巢蛋白NID2抗體
xy-9712R    NHEDC2線(xiàn)粒體鈉/氫交換蛋白質(zhì)2抗體
xy-8570R    Neurogenin 1神經(jīng)元素1抗體
xy-0071R    Neuropeptide Y神經(jīng)肽Y抗體
xy-0073R    Neurturin神經(jīng)營(yíng)養(yǎng)因子抗體
xy-0222R    NMDAR2B谷氨酸受體2B抗體
xy-0694R    Neuropilin 2神經(jīng)纖毛蛋白2抗體
xy-1072R    NR2D谷氨酸受體2D抗體
xy-1146R    NRAS原癌基因N-Ras抗體
xy-6461R    NF-ATc4T細(xì)胞激活核轉(zhuǎn)錄因子4抗體
xy-8588R    NETO1腦低密度脂蛋白受體蛋白1抗體
xy-11104R    Neurexin 2軸突蛋白2抗體
xy-4866R    Nephrin腎小球細(xì)胞粘附分子受體抗體
xy-11095R    NEGR1神經(jīng)生長(zhǎng)調(diào)節(jié)蛋白1抗體