葡萄膜自身抗原Uaca抗體 返回列表頁

葡萄膜自身抗原Uaca抗體

文名稱 UACA
中文名稱 葡萄膜自身抗原Uaca抗體
別    名 Uaca; Kiaa1561; Conflict; Uveal autoantigen with coiled coil domains and ankyrin repeats; Uveal autoantigen with coiled-coil domains and ankyrin repeats; Nuclear membrane-binding protein; Nucling.
 
說 明 書 0.2ml  
研究領域 心血管  細胞生物  信號轉導  細胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Cow, Horse, Rabbit, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 156kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human UACA
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation,LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation.Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility.Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).

Function:
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1. 
Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury.

Subunit:
Component of the apoptosome complex, composed of APAF1, pro-caspase-9 and UACA. In the complex, it probably interacts directly with APAF1. Interacts with LGALS3, ARF6 and ACTB.xy-12314R    NKX6.1轉錄因子相關蛋白NKX6.1抗體
xy-12345R    NCKAP1L造血蛋白1抗體
xy-10075R    Nidogen2骨巢蛋白抗體
xy-4028R    NUP54NUP54抗體
xy-3695R    NTF97親核素β1抗體
xy-7124R    NMDA epsilon 1谷氨酸受體NMDAζ1抗體
xy-8483R    NMDA epsilon 2谷氨酸受體NMDAζ2抗體
xy-3692R    Neurogenin 2神經元素2抗體
xy-3688R    NDRG3抑癌基因NDRG3抗體
xy-3682R    有絲分裂氧化酶1抗體
xy-3683R    NADPH oxidase 3NADPH oxidase 3抗體
xy-3684R    NADPH oxidase 4NADPH氧化酶NOX家族的成員4抗體
xy-7714R    CDCA1細胞分裂周期相關蛋白1抗體
xy-2680R    NFAM1NFAM1抗體
xy-11897R    NEURL環(huán)指蛋白67抗體
xy-6043R    NBL1神經母細胞瘤抑瘤蛋白1抗體
xy-3886R    NCF1嗜中性粒細胞胞漿因子1抗體
xy-3888R    NDUFS3線粒體復合物NDUFS3蛋白抗體
xy-6210R    NRIP雄激素受體復合物相關蛋白/核受體相互作用蛋白抗體
xy-4210R    C9orf1569號染色體開放閱讀框156抗體
xy-2952R    NFAT4核因子活化T細胞胞漿蛋白3抗體
xy-6552R    NANOGP8干細胞轉錄因子NANOGP8抗體
xy-5804R    NAIP神經細胞凋亡抑制蛋白抗體
xy-6721R    NLG1腎病樣蛋白2抗體
xy-5811R    NUAK2SNF1/AMP激酶相關激酶2抗體
xy-4814R    Newcastle disease virus雞新城疫疫苗（雞瘟4型混合病毒）抗體
xy-11170R    NXPH1神經外營養(yǎng)蛋白1抗體
xy-11502R    NENF神經源性神經營養(yǎng)因子抗體
xy-11533R    Proprotein Convertase 2神經內分泌轉化酶2抗體
xy-11531R    NPW/Neuropeptide W神經肽W抗體
xy-11521R    NPY5R神經肽Y受體5抗體
xy-11522R    NPY4R神經肽Y受體4抗體
xy-11523R    NHLH1 + NHLH2螺旋環(huán)螺旋蛋白1+2抗體