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泛素蛋白連接酶E3抗體

英文名稱 UBE2E3
中文名稱 泛素蛋白連接酶E3抗體
別    名 Homologous to yeast UBC4/5; UB2E3_HUMAN; UBC E4; Ubc M2; UBC4/5 homolog; UBCE 4; UBCE4; UBCH 9; UBCH9; UbcM2; UBE2 E3; UBE2E3; Ubiquitin carrier protein; Ubiquitin carrier protein E3; Ubiquitin conjugating enzyme E2 23 kDa; Ubiquitin conjugating enzyme E2 E3; Ubiquitin conjugating enzyme E2E 3; Ubiquitin conjugating enzyme UBCH 9; Ubiquitin conjugating enzyme UBCH9; Ubiquitin protein ligase; Ubiquitin protein ligase E3; Ubiquitin-conjugating enzyme E2 E3; Ubiquitin-conjugating enzyme E2-23 kDa; Ubiquitin-protein ligase E3.
 
說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
細(xì)胞定位 細(xì)胞核 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human UBE2E3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.

Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.

Subunit:
The ubiquitin-loaded form interacts specifically with importin-11 (IPO11), leading to its import into the nucleus (By similarity). Interacts with NEDD4L.

Subcellular Location:
Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.

Tissue Specificity:xy-5105R    PRPS1L1蛋白酶體復(fù)合物C5抗體
xy-2310R    recPEP重組豬乙腦病毒結(jié)構(gòu)蛋白抗體
xy-5371R    PMVK磷酸甲羥戊酸激酶抗體
xy-12275R    PREI3Phocein蛋白抗體
xy-12260R    PSMA4蛋白酶體PSMα4/20S Proteasome α4抗體
xy-4728R    Prion protein PrP朊病毒/感染性蛋白抗體
xy-0451R    PIP5KL14-磷酸磷脂酰肌醇5激酶1樣蛋白抗體
xy-10278R    phospho-PIK3 gamma (Thr1024)磷酸化磷脂酰肌醇激酶PIK3-γ抗體
xy-12296R    PBX1B淋巴細(xì)胞白血病前體蛋白轉(zhuǎn)錄因子1抗體
xy-12297R    PBX2B淋巴細(xì)胞白血病前體蛋白轉(zhuǎn)錄因子2抗體
xy-12298R    PBX4B淋巴細(xì)胞白血病前體蛋白轉(zhuǎn)錄因子4抗體
xy-12246R    Pumilio 2PUM2蛋白抗體
xy-12288R    PMFBP1多胺調(diào)制因子結(jié)合蛋白1抗體
xy-12295R    PBX3B淋巴細(xì)胞白血病前體蛋白轉(zhuǎn)錄因子3抗體
xy-5091R    PHYHIP植烷酸氧化酶抗體
xy-5090R    P4HB蛋白二硫鍵異構(gòu)酶P4HB抗體
xy-2371R    PKA C alpha+beta蛋白激酶C抗體
xy-11685R    PHF-tau成對(duì)螺旋細(xì)絲蛋白抗體
xy-2364R    PITX3炎癥因子3抗體（穿透素）
xy-11932R    Pecanex山核桃素樣蛋白1抗體
xy-4055R    phospho-PPAR alpha (Ser12)磷酸化α型-過(guò)氧化酶活化增生受體抗體
xy-11161R    PCDHGC5原鈣粘蛋白γC5抗體
xy-4203R    PDZ RHOGEFRho鳥(niǎo)甘酸轉(zhuǎn)運(yùn)蛋白抗體
xy-3725R    Phospho-PRKACB(Thr198)磷酸化蛋白激酶C亞性抗體
xy-3728R    phospho-PKC delta (Tyr311)磷酸化蛋白激酶C亞性D型抗體
xy-3626R    SCA14蛋白激酶C亞型G抗體
xy-3729R    Phospho-PKC gamma (Thr514)磷酸化蛋白激酶C亞型G抗體
xy-3730R    Phospho-PKC gamma (Thr674)磷酸化蛋白激酶C亞型G抗體
xy-3627R    PRL1肝再生磷酸酯酶1抗體
xy-3628R    PRL3磷酸酯酶3蛋白抗體
xy-5005R    PFKFB2果糖-2,6-二磷酸酶心肌酶抗體
xy-5006R    PGAM1 磷酸變位酶1抗體
xy-2335R    PGK1磷酸激酶1抗體
xy-5000R    PCB丙酮酸羧化酶抗體
xy-5003R    PDHX丙酮酸脫氫酶復(fù)合物X蛋白抗體
Ubiquitously expressed at low levels. Highly expressed in skeletal muscle.

Similarity:
Belongs to the ubiquitin-conjugating enzyme family.