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跨膜前列腺雄激素誘導(dǎo)蛋白1抗體

英文名稱 TMEPAI
中文名稱 跨膜前列腺雄激素誘導(dǎo)蛋白1抗體
別    名 PMEPA_HUMAN; PMEPA1; Prostate transmembrane protein, androgen induced 1; Solid tumor associated 1 protein; Solid tumor-associated 1 protein; STAG1; TMEPAI; Transmembrane prostate androgen induced protein; Transmembrane prostate androgen-induced protein; Transmembrane, prostate androgen induced RNA.

說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細胞生物  信號轉(zhuǎn)導(dǎo)  生長因子和激素  跨膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TMEPAI
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Function:
Involved in down-regulation of the androgen receptor (AR). Enhances ubiquitination and proteasome-mediated degradation of AR, probably by recruiting NEDD4.

Subcellular Location:
Cell membrane.xy-10108R    phospho-Tau protein (Ser579)磷酸化微管相關(guān)蛋白抗體
xy-10109R    phospho-Tau protein(Ser531)磷酸化微管相關(guān)蛋白抗體
xy-10110R    phospho-Tau protein(Ser516)磷酸化微管相關(guān)蛋白抗體
xy-10111R    phospho-Tau protein(Ser552)磷酸化微管相關(guān)蛋白抗體
xy-10112R    phospho-Tau protein(Thr529)磷酸化微管相關(guān)蛋白抗體
xy-10113R    phospho-Tau protein(Thr522)磷酸化微管相關(guān)蛋白抗體
xy-10114R    phospho-Tau protein(Ser673)磷酸化微管相關(guān)蛋白抗體
xy-10115R    phospho-Tau protein(Ser733)磷酸化微管相關(guān)蛋白抗體
xy-10116R    phospho-Tau protein(Ser519)磷酸化微管相關(guān)蛋白抗體
xy-11437R    TRAP80MED17抗體
xy-11438R    TRIP13甲狀腺激素受體相互作用13/乳頭瘤病毒16型E1結(jié)合蛋白抗體
xy-11440R    THRB1甲狀腺激素受體β抗體(THβ1，THβ2)
xy-7508R    THSD1血小板跨膜反應(yīng)蛋白1抗體
xy-4690R    CD142組織因子抗體
xy-5725R    TNFSF13腫瘤壞死因子配體超家族成員13抗體
xy-6607R    TSPY1睪丸特異定蛋白質(zhì)編碼Y1抗體
xy-6241R    TM4SF3跨膜蛋白4超家族成員3抗體
xy-6601R    TLR7Toll樣受體7抗體
xy-6240R    TLX3T細胞白血病同源盒蛋白3抗體
xy-5707R    TUSC2血小板源性生長因子A相關(guān)蛋白2抗體
xy-11694R    TMEM106B跨膜蛋白106B抗體
xy-11688R    Tau421微管相關(guān)蛋白Tau421抗體
xy-11980R    CABP4瞬時受體電位通道蛋白4抗體
xy-7955R    TPTE腫瘤/睪丸抗原44抗體
xy-7939R    TACC1乳腺癌、胃癌抗原GA55抗體
xy-7924R    TBRG4轉(zhuǎn)化生長因子β調(diào)節(jié)蛋白4抗體
xy-6914R    TYK3酪氨酸蛋白激酶3抗體
xy-7911R    phospho-TYK3(Tyr402)磷酸化酪氨酸蛋白激酶3抗體
xy-9049R    TRPM1瞬時受體電位離子通道蛋白1抗體（M亞家族）
xy-9048R    TRPM6瞬時受體電位離子通道蛋白6抗體（M亞家族）
xy-8059R    TMEM2L跨膜蛋白2樣蛋白抗體
xy-11240R    phospho-Tau protein(Ser202)磷酸化微管相關(guān)蛋白抗體
xy-11236R    Lefty轉(zhuǎn)化生長因子β4抗體TGF β4
xy-11237R    TCF12轉(zhuǎn)錄因子12抗體
xy-11262R    TMP21跨膜轉(zhuǎn)運蛋白21抗體