血管內(nèi)皮細(xì)胞生長(zhǎng)抑制蛋白vegi抗體 返回列表頁(yè)

血管內(nèi)皮細(xì)胞生長(zhǎng)抑制蛋白vegi抗體

英文名稱 TL1A
中文名稱 血管內(nèi)皮細(xì)胞生長(zhǎng)抑制蛋白vegi抗體
別    名 MGC129934; MGC129935; TL1 A; tl1; tl1a; tnf ligand related molecule 1; TNF ligand-related molecule 1; tnf superfamily ligand tl1a; TNF15_HUMAN; tnfsf15; Tumor necrosis factor (ligand) superfamily member 15; Tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15, secreted form; Vascular endothelial cell growth inhibitor; Vascular endothelial growth inhibitor 192a; Vascular endothelial growth inhibitor; vegi; VEGI192A.

說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
細(xì)胞定位 細(xì)胞膜 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TL1A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

Function:
Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.

Subunit:
Homotrimer. 

Subcellular Location:
Secreted and Membrane.xy-1950R    VAMP1VAMP1囊泡相關(guān)膜蛋白1抗體
xy-1951R    VAMP2囊泡相關(guān)膜蛋白2抗體
xy-8002R    VGAT氨基丁酸轉(zhuǎn)運(yùn)蛋白VGAT抗體
xy-7410R    V-ATPase A1氫離子轉(zhuǎn)運(yùn)ATP合成酶A1抗體
xy-3603R    VASP血管擴(kuò)張刺激磷蛋白抗體
xy-3465R    Phospho-VASP(Ser157)磷酸化血管擴(kuò)張刺激磷蛋白抗體
xy-3468R    phospho-VEGFR2 (Tyr1175)磷酸化血管內(nèi)皮生長(zhǎng)因子受體2抗體
xy-3469R    phospho-VEGF receptor 2 (Tyr1214)磷酸化血管內(nèi)皮生長(zhǎng)因子受體2抗體
xy-3470R    phospho-VEGF receptor 2 (Tyr996)磷酸化血管內(nèi)皮生長(zhǎng)因子受體2抗體
xy-0396R    VCAM-1血管內(nèi)皮細(xì)胞粘附分子抗體
xy-13854R    Valine纈氨酸抗體
xy-10529R    VAP1血管粘附蛋白1抗體
xy-13741R    Vinexin細(xì)胞間粘附蛋白Vinexin抗體
xy-8533R    Vimentin波形蛋白抗體
xy-13855R    Vitamin A維生素A抗體
xy-2533R    Versican蛋白聚糖Versican抗體
xy-2169R    VWCEVWCE抗體
xy-11496R    VAX1視神經(jīng)視網(wǎng)膜相關(guān)蛋白VAX1抗體
xy-11497R    VAX2視神經(jīng)視網(wǎng)膜相關(guān)蛋白VAX2抗體
xy-2987R    Vitamin D Receptor/VDR維生素D3受體抗體
xy-12326R    VPREB1B淋巴細(xì)胞前體蛋白1抗體
xy-8994R    VCAM-1血管內(nèi)皮細(xì)胞粘附分子抗體
xy-12340R    VNN2血管非炎性蛋白2抗體
xy-7883R    VHLH腦視網(wǎng)膜血管瘤G7蛋白抗體（逢希伯-林道氏病）
xy-11167R    VGLUT1/BNP1腦特異性鈉依賴無(wú)機(jī)磷轉(zhuǎn)運(yùn)蛋白抗體
xy-9565R    VMAT2腦單胺類神經(jīng)遞質(zhì)轉(zhuǎn)運(yùn)蛋白抗體
xy-1367R    VHL腦視網(wǎng)膜血管瘤G7蛋白抗體（逢希伯-林道氏?。?br>xy-9465R    VANGL2神經(jīng)管畸形相關(guān)蛋白VANGL2抗體
xy-3466R    Phospho-VASP(Ser239)磷酸化血管擴(kuò)張刺激磷蛋白抗體
xy-3467R    phospho-VEGF receptor 2 (Tyr1059)磷酸化血管內(nèi)皮生長(zhǎng)因子受體2抗體
xy-0926R    V.cholera Ogawa01群小川型霍亂弧菌抗體
xy-10427R    VAMP-1+2+3囊泡相關(guān)膜蛋白1,2,3抗體
xy-10332R    VGF/NERP2神經(jīng)內(nèi)分泌調(diào)節(jié)肽VGF抗體
xy-2309R    VP2重組豬細(xì)小病毒VP2蛋白抗體
xy-2742R    VEGF-D血管內(nèi)皮生長(zhǎng)因子D型抗體
xy-2806R    VDCC-L alphaL-型電壓依賴型鈣通道α抗體