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結(jié)節(jié)漏斗肽TIP39抗體

英文名稱 TIP39/Tuberoinfundibular peptide
中文名稱 結(jié)節(jié)漏斗肽TIP39抗體
別    名 TIP39; TIPF39; Tuberoinfundibular peptide of 39 residues.
  
說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Dog, Cow, 
產(chǎn)品應(yīng)用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TIP39/Tuberoinfundibular peptide
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Tuberoinfundibular peptide of 39 residues (TIP39) was initially identified as a neurotransmitter and agonist of the PTH2 receptor, which is expressed in the cardiovascular system. Accumulating evidence suggests that TIP39 may be the endogenous ligand of the parathyroid hormone 2 receptor. The vast majority of TIP39 containing neurons are localized in two regions, the subparafascicular area at the thalamic midbrain junction, and the medial paralemniscal nucleus in the rostral pons. In contrast to the restricted localization of TIP39 containing cell bodies, TIP39 containing fibers have a widespread distribution.

Function:
Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization. May inhibit cell proliferation via its action on PTH2R activation. Neuropeptide which may also have a role in spermatogenesis. May activate nociceptors and nociceptive circuits.xy-0308R    Rabbit Anti-horse IgG兔抗馬IgG
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四、標(biāo)記二抗    
    
編號(hào)    名 稱
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