疣狀表皮發(fā)育不良蛋白1抗體 返回列表頁

疣狀表皮發(fā)育不良蛋白1抗體

英文名稱 TMC6
中文名稱 疣狀表皮發(fā)育不良蛋白1抗體
別    名 Epidermodysplasia verruciformis protein 1; EV1; EVER1; EVIN1; TMC6_HUMAN; LAK 4P; LAK4P; Protein LAK 4; Protein LAK4; Transmembrane channel like protein 6.
 
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  跨膜蛋白  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 90kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TMC6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs. [provided by RefSeq, Jul 2008]

Function:
Defects in TMC6 are a cause of epidermodysplasia verruciformis, a rare autosomal recessive genodermatosis associated with a high risk of skin carcinoma that results from an abnormal susceptibility to infection by specific human papillomaviruses. Infection leads to persistent wart-like or macular lesions. TMC6 is expressed in placenta, prostate, testis, activated T-lymphocytes and lymphokine-activated killer (LAK) lymphocytes. There are four named isoforms.xy-0326G-HRxy    Goat Anti-Bovine IgG/HRP辣根過氧化物酶標(biāo)記的羊抗牛IgG
xy-0311R-HRxy    Rabbit Anti-Biotin/HRP辣根過氧化物酶標(biāo)記的兔抗生物素抗體IgG
xy-0327R-FITxy    Rabbit Anti-Bovine IgM/FITCFITC標(biāo)記的兔抗牛IgM
xy-0326R-FITxy    Rabbit Anti-Bov IgG/FITCFITC標(biāo)記的兔抗牛IgG
xy-0327R-RBITxy    Rabbit Anti-Bovine IgM/RBITC羅丹明標(biāo)記的兔抗牛IgM
xy-0326G-xyE    Goat Anti-Bovine IgG/PEPE標(biāo)記的羊抗牛IgG
xy-0327R-xyE    Rabbit Anti-Bovine IgM/PEPE標(biāo)記的兔抗牛IgM
xy-0326R-AF647    Rabbit Anti-Bov IgG/Alexa Fluor 647Alexa Fluor 647標(biāo)記的兔抗牛IgG
xy-0326R-xyE-xyy5.5    Rabbit Anti-Bov IgG/PE-Cy5.5PE-Cy5.5標(biāo)記的兔抗牛IgG
xy-0327R-xyE-xyy5.5    Rabbit Anti-Bovine IgM/PE-Cy5.5PE-Cy5.5標(biāo)記的兔抗牛IgM
xy-0327R-xyE-xyy7    Rabbit Anti-Bovine IgM/PE-Cy7PE-Cy7標(biāo)記的兔抗牛IgM
xy-0326G-xyy3    Goat Anti-Bovine IgG/Cy3Cy3標(biāo)記的羊抗牛IgG
xy-0310G-AF647    Goat Anti-Chicken IgG/Alexa Fluor 647Alexa Fluor 647標(biāo)記的羊抗雞IgG
xy-0310G-AF488    Goat Anti-Chicken IgG/Alexa Fluor 488Alexa Fluor 488標(biāo)記的羊抗雞IgG
xy-0310R-FITxy    Rabbit Anti-chicken IgG/FITCFITC標(biāo)記的兔抗雞IgG
xy-0310R-HRxy    Rabbit Anti-chicken IgG/HRP辣根過氧化物酶標(biāo)記的兔抗雞IgG
xy-0310R-AF350    Rabbit Anti-chicken IgG/Alexa Fluor 350Alexa Fluor 350標(biāo)記的兔抗雞IgG
xy-0310R-AF488    Rabbit Anti-chicken IgG/Alexa Fluor 488Alexa Fluor 488標(biāo)記的兔抗雞IgG
xy-0295xy-HRxy    Donkey Anti-rabbit IgG/HRP辣根過氧化物酶標(biāo)記的驢抗兔IgG
xy-0295xy-FITxy    Donkey Anti-rabbit IgG/FITCFITC標(biāo)記的驢抗兔IgG
xy-0295xy-Axy    Donkey Anti-rabbit IgG/AP堿性磷酸酶（AP）標(biāo)記的驢抗兔IgG
xy-0295xy-xyy5    Donkey Anti-rabbit IgG/Cy5Cy5標(biāo)記的驢抗兔IgG
xy-0295xy-AF488    Donkey Anti-rabbit IgG/Alexa Fluor 488Alexa Fluor 488標(biāo)記的驢抗兔IgG
xy-0295xy-AF555    Donkey Anti-rabbit IgG/Alexa Fluor 555Alexa Fluor 555標(biāo)記的驢抗兔IgG
xy-0295xy-AF647    Donkey Anti-rabbit IgG/Alexa Fluor 647Alexa Fluor 647標(biāo)記的驢抗兔IgG
xy-0303R-xyE    Rabbit Anti-dog IgG/PEPE標(biāo)記的兔抗狗IgG
xy-0295xy-Bio    Donkey Anti-rabbit IgG/Bio生物素標(biāo)記的驢抗兔IgG