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TBP相互作用蛋白TIP120A抗體

英文名稱 TIP120A
中文名稱 TBP相互作用蛋白TIP120A抗體
別    名 CAND 1; Cand1; CAND1_HUMAN; Cullin associated and neddylation dissociated 1; Cullin associated and neddylation dissociated protein 1; Cullin associated NEDD8 dissociated protein 1; Cullin-associated and neddylation-dissociated protein 1; Cullin-associated NEDD8-dissociated protein 1; DKFZP434M1414; FLJ10114; FLJ10929; FLJ38691; FLJ90441; KIAA0829; p120 CAND1; TATA binding protein interacting protein 120A; TBP interacting protein; TBP interacting protein of 120 kDa A; TBP Interacting Protein TIP120A; TBP-interacting protein 120A; TBP-interacting protein of 120 kDa A; TIP120; TIP120 protein.

說 明 書 0.2ml  
研究領域 細胞生物  表觀遺傳學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Pig, Cow, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 136kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TIP120A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 Function:
Enhances transcription from various types of promoters (By similarity). Regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. Prevents neddylation of CUL1 by physically blocking access to the neddylation site. Disrupts interactions between CUL1 and SKP1 and between CUL1 and F-box proteins.

Subunit:
Interacts with TBP (By similarity). Part of a complex that contains CUL1 and RBX1. Interacts with unneddylated cullins: interacts with CUL1, CUL2, CUL3, CUL4A, CUL4B and CUL5. Does not bind neddylated CUL1. Interaction with cullins is abolished in presence of COMMD1, which antagonizes with CAND1 for interacting with cullins.

Subcellular Location:
Cytoplasm Nucleus.

Similarity:
Belongs to the CAND family.
Contains 27 HEAT repeats.

Gene ID:
55832xy-0308R-xyE-xyY5    Rabbit Anti-horse IgG/PE-CY5PE-CY5標記的兔抗馬IgG
xy-0308R-xyy3    Rabbit Anti-horse IgG/Cy3Cy3標記的兔抗馬IgG
xy-0308R-xyy5    Rabbit Anti-horse IgG/Cy5Cy5標記的兔抗馬IgG
xy-0308R-xyy5.5    Rabbit Anti-horse IgG/Cy5.5Cy5.5標記的兔抗馬IgG
xy-0308R-xyy7    Rabbit Anti-horse IgG/Cy7Cy7標記的兔抗馬IgG
xy-0308R-xyE    Rabbit Anti-horse IgG/PEPE標記的兔抗馬IgG
xy-0297R-RBITxy    Rabbit Anti-human IgG/RBITC羅丹明標記的兔抗人IgG
xy-0297R-Golxy    Rabbit Anti-human IgG/Gold膠體金標記的兔抗人IgG
xy-0297R-Axy    Rabbit Anti-human IgG/AP堿性磷酸酶（AP）標記的兔抗人IgG
xy-0297R-xyE-xyy5.5    Rabbit Anti-human IgG/PE-Cy5.5PE-Cy5.5標記的兔抗人IgG
xy-0297R-xyE-xyy7    Rabbit Anti-human IgG/PE-Cy7PE-Cy7標記的兔抗人IgG
xy-0297R-Axyxy    Rabbit Anti-human IgG/APCAPC標記的兔抗人IgG
xy-0297R-AF350    Rabbit Anti-human IgG/Alexa Fluor 350Alexa Fluor 350標記的兔抗人IgG
xy-0297R-AF488    Rabbit Anti-human IgG/Alexa Fluor 488Alexa Fluor 488標記的兔抗人IgG
xy-0297R-AF555    Rabbit Anti-human IgG/Alexa Fluor 555Alexa Fluor 555標記的兔抗人IgG
xy-0297R-xyy3    Rabbit Anti-human IgG/Cy3Cy3標記的兔抗人IgG
xy-0297R-xyy5    Rabbit Anti-human IgG/Cy5Cy5標記的兔抗人IgG
xy-0297R-xyE    Rabbit Anti-human IgG/PEPE標記的兔抗人IgG
xy-0297R-xyE-xyy3    Rabbit Anti-human IgG/PE-Cy3PE-Cy3標記的兔抗人IgG
xy-0297R-xyy5.5    Rabbit Anti-human IgG/Cy5.5Cy5.5標記的兔抗人IgG
xy-0297R-xyy7    Rabbit Anti-human IgG/Cy7Cy7標記的兔抗人IgG
xy-0345R-RBITxy    Rabbit Anti-human IgM/RBITC羅丹明標記的兔抗人IgM
xy-0345R-Bio    Rabbit Anti-human IgM/Bio生物素標記的兔抗人IgM
xy-0345R-HRxy    Rabbit Anti-human IgM/HRP辣根過氧化物酶標記的兔抗人IgM
xy-0345R-Axy    Rabbit Anti-human IgM/AP堿性磷酸酶（AP）標記的兔抗人IgM
xy-0345R-Golxy    Rabbit Anti-human IgM/Gold膠體金標記的兔抗人IgM
xy-0345R-FITxy    Rabbit Anti-human IgM/FITCFITC標記的兔抗人IgM
xy-0345R-xyy3    Rabbit Anti-human IgM/Cy3Cy3標記的兔抗人IgM
xy-0345R-xyy5    Rabbit Anti-human IgM/Cy5Cy5標記的兔抗人IgM
xy-0345R-xyy5.5    Rabbit Anti-human IgM/Cy5.5Cy5.5標記的兔抗人IgM
xy-0345R-xyy7    Rabbit Anti-human IgM/Cy7Cy7標記的兔抗人IgM
xy-0345R-xyE    Rabbit Anti-human IgM/PEPE標記的兔抗人IgM
xy-0345R-xyE-xyy3    Rabbit Anti-human IgM/PE-Cy3PE-Cy3標記的兔抗人IgM
xy-0345R-xyE-xyY5    Rabbit Anti-human IgM/PE-CY5PE-CY5標記的兔抗人IgM