磷酸化DNA拓普西異構(gòu)酶Ⅱ抗體 返回列表頁

磷酸化DNA拓普西異構(gòu)酶Ⅱ抗體

英文名稱 phospho-Topoisomerase II alpha (Ser1525)
中文名稱 磷酸化DNA拓普西異構(gòu)酶Ⅱ抗體
別    名 Topoisomerase II alpha (phospho S1525); alpha isozyme; ATP hydrolyzing DNA topoisomerase II alfa; DNA gyrase; DNA topoisomerase 2 alpha; DNA topoisomerase 2-alpha; DNA topoisomerase II 170 kD; DNA topoisomerase II alpha isozyme; DNA topoisomerase II; DNA Topoisomerase2; TOP 2A; TOP2; TOP2A; TOP2A_HUMAN; Topoisomerase DNA II alpha 170kDa; TP2A.

說 明 書 0.1ml  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 細胞生物  發(fā)育生物學(xué)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 174kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Topoisomerase II alpha around the phosphorylation site of Ser1525
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-angiectasia. [provided by RefSeq, Jul 2010]

Function:
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.xy-0296R-Golxy    Rabbit Anti-mouse IgG/Gold膠體金標(biāo)記的兔抗小鼠IgG
xy-0296R-Axy    Rabbit Anti-mouse IgG/AP堿性磷酸酶（AP）標(biāo)記的兔抗小鼠IgG
xy-0296R-Bio    Rabbit Anti-mouse IgG/Bio生物素標(biāo)記的兔抗小鼠IgG
xy-0296R-xyy3    Rabbit Anti-mouse IgG/Cy3Cy3標(biāo)記的兔抗小鼠IgG
xy-0296R-xyy5.5    Rabbit Anti-mouse IgG/Cy5.5Cy5.5標(biāo)記的兔抗小鼠IgG
xy-0296R-xyy7    Rabbit Anti-mouse IgG/Cy7Cy7標(biāo)記的兔抗小鼠IgG
xy-0296R-xyE    Rabbit Anti-mouse IgG/PEPE標(biāo)記的兔抗小鼠IgG
xy-0296R-xyE-xyy3    Rabbit Anti-mouse IgG/PE-Cy3PE-Cy3標(biāo)記的兔抗小鼠IgG
xy-0296R-xyE-xyY5    Rabbit Anti-mouse IgG/PE-CY5PE-CY5標(biāo)記的兔抗小鼠IgG
xy-0296R-Axyxy    Rabbit Anti-mouse IgG/APCAPC標(biāo)記的兔抗小鼠IgG
xy-0296R-AF488    Rabbit Anti-mouse IgG/Alexa Fluor 488Alexa Fluor 488標(biāo)記的兔抗小鼠IgG
xy-0296R-AF555    Rabbit Anti-mouse IgG/Alexa Fluor 555Alexa Fluor 555標(biāo)記的兔抗小鼠IgG
xy-0296R-xyE-xyy5.5    Rabbit Anti-mouse IgG/PE-Cy5.5PE-Cy5.5標(biāo)記的兔抗小鼠IgG
xy-0296R-xyE-xyy7    Rabbit Anti-mouse IgG/PE-Cy7PE-Cy7標(biāo)記的兔抗小鼠IgG
xy-0368R-Bio    Rabbit Anti-mouse IgM/Bio生物素標(biāo)記的兔抗小鼠IgM
xy-0368R-HRxy    Rabbit Anti-mouse IgM/HRP辣根過氧化物酶標(biāo)記的兔抗小鼠IgM
xy-0368R-xyy5    Rabbit Anti-mouse IgM/Cy5Cy5標(biāo)記的兔抗小鼠IgM
xy-0368R-xyy5.5    Rabbit Anti-mouse IgM/Cy5.5Cy5.5標(biāo)記的兔抗小鼠IgM
xy-0368R-xyy7    Rabbit Anti-mouse IgM/Cy7Cy7標(biāo)記的兔抗小鼠IgM
xy-0368R-xyE    Rabbit Anti-mouse IgM/PEPE標(biāo)記的兔抗小鼠IgM
xy-0368R-AF647    Rabbit Anti-mouse IgM/Alexa Fluor 647Alexa Fluor 647標(biāo)記的兔抗小鼠IgM
xy-0368R-Axyxy    Rabbit Anti-mouse IgM/APCAPC標(biāo)記的兔抗小鼠IgM
xy-0368R-Golxy    Rabbit Anti-mouse IgM/Gold膠體金標(biāo)記的兔抗小鼠IgM
xy-0368R-AF350    Rabbit Anti-mouse IgM/Alexa Fluor 350Alexa Fluor 350標(biāo)記的兔抗小鼠IgM
xy-0368R-AF488    Rabbit Anti-mouse IgM/Alexa Fluor 488Alexa Fluor 488標(biāo)記的兔抗小鼠IgM
xy-0368R-xyy3    Rabbit Anti-mouse IgM/Cy3Cy3標(biāo)記的兔抗小鼠IgM
xy-0368R-FITxy    Rabbit Anti-mouse IgM/FITCFITC標(biāo)記的兔抗小鼠IgM
xy-0368R-RBITxy    Rabbit Anti-mouse IgM/RBITC羅丹明標(biāo)記的兔抗小鼠IgM
xy-0330R-RBITxy    Rabbit anti-mouse Kappa light chain/RBITC羅丹明標(biāo)記的兔抗小鼠k鏈
xy-0330R-Axy    Rabbit anti-mouse Kappa light chain/AP堿性磷酸酶（AP）標(biāo)記的兔抗小鼠k鏈
xy-0330R-FITxy    Rabbit anti-mouse Kappa light chain/FITCFITC標(biāo)記的兔抗小鼠k鏈
xy-0330R-Golxy    Rabbit anti-mouse Kappa light chain/Gold膠體金標(biāo)記的兔抗小鼠k鏈
xy-0330R-xyy3    Rabbit anti-mouse Kappa light chain/Cy3Cy3標(biāo)記的兔抗小鼠k鏈
xy-0330R-xyy5    Rabbit anti-mouse Kappa light chain/Cy5Cy5標(biāo)記的兔抗小鼠k鏈