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T淋巴細胞膜蛋白3抗體

英文名稱 TIM 3
中文名稱 T淋巴細胞膜蛋白3抗體
別    名 TIM-3; HAVR2_MOUSE; Hepatitis A virus cellular receptor 2; Kidney injury molecule 3; KIM 3; KIM3; T cell immunoglobulin and mucin domain containing 3; T cell immunoglobulin mucin 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim 3; TIM-3; TIM3; TIMD-3; TIMD3.
 
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細胞生物  免疫學(xué)  淋巴細胞  t-淋巴細胞  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse TIM 3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011] 

Function:
Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.

Subcellular Location:
Membrane.

Tissue Specificity:
T-helper type 1 lymphocyte (Th1)-specific.

Post-translational modifications:
O-glycosylated with core 1 or possibly core 8 glycans.

Similarity:
Belongs to the immunoglobulin superfamily. TIM family.

Gene ID:
171285

Database links:

Entrez Gene: 171285 Mouse

SwissProt: Q8VIM0 Mouse

Unigene: 72168 Mousexy-0777R-Bio    Rabbit Anti-Mink IgG/Bio生物素標記的兔抗水貂IgG
xy-0777R-xyy3    Rabbit Anti-Mink IgG/Cy3Cy3標記的兔抗水貂IgG
xy-0777R-xyy5    Rabbit Anti-Mink IgG/Cy5Cy5標記的兔抗水貂IgG
xy-0777R-xyy5.5    Rabbit Anti-Mink IgG/Cy5.5Cy5.5標記的兔抗水貂IgG
xy-0777R-xyy7    Rabbit Anti-Mink IgG/Cy7Cy7標記的兔抗水貂IgG
xy-0777R-xyE    Rabbit Anti-Mink IgG/PEPE標記的兔抗水貂IgG
xy-0777R-xyE-xyy3    Rabbit Anti-Mink IgG/PE-Cy3PE-Cy3標記的兔抗水貂IgG
xy-0777R-xyE-xyY5    Rabbit Anti-Mink IgG/PE-CY5PE-CY5標記的兔抗水貂IgG
xy-0777R-Axyxy    Rabbit Anti-Mink IgG/APCAPC標記的兔抗水貂IgG
xy-0777R-AF350    Rabbit Anti-Mink IgG/Alexa Fluor 350Alexa Fluor 350標記的兔抗水貂IgG
xy-0777R-AF488    Rabbit Anti-Mink IgG/Alexa Fluor 488Alexa Fluor 488標記的兔抗水貂IgG
xy-0777R-AF555    Rabbit Anti-Mink IgG/Alexa Fluor 555Alexa Fluor 555標記的兔抗水貂IgG
xy-0777R-AF647    Rabbit Anti-Mink IgG/Alexa Fluor 647Alexa Fluor 647標記的兔抗水貂IgG
xy-0777R-xyE-xyy5.5    Rabbit Anti-Mink IgG/PE-Cy5.5PE-Cy5.5標記的兔抗水貂IgG
xy-0777R-xyE-xyy7    Rabbit Anti-Mink IgG/PE-Cy7PE-Cy7標記的兔抗水貂IgG
xy-0777R-Axy    Rabbit Anti-Mink IgG/AP堿性磷酸酶（AP）標記的兔抗水貂IgG
xy-0777R-FITxy    Rabbit Anti-Mink IgG/FITCFITC標記的兔抗水貂IgG
xy-0777R-RBITxy    Rabbit Anti-Mink IgG/RBITC羅丹明標記的兔抗水貂IgG
xy-0777R-Golxy    Rabbit Anti-Mink IgG/Gold膠體金標記的兔抗水貂IgG
xy-0297xy-RBITxy    Donkey Anti-human IgG/RBITC羅丹明標記的驢抗人IgG
xy-0297xy-Golxy    Donkey Anti-human IgG/Gold膠體金標記的驢抗人IgG
xy-0297xy-FITxy    Donkey Anti-human IgG/FITCFITC標記的驢抗人IgG
xy-0297xy-Axy    Donkey Anti-human IgG/AP堿性磷酸酶（AP）標記的驢抗人IgG
xy-0297xy-HRxy    Donkey Anti-human IgG/HRP辣根過氧化物酶標記的驢抗人IgG
xy-0297xy-Bio    Donkey Anti-human IgG/Bio生物素標記的驢抗人IgG
xy-0297xy-AF555    Donkey Anti-human IgG/Alexa Fluor 555Alexa Fluor 555標記的驢抗人IgG
xy-0297xy-AF647    Donkey Anti-human IgG/Alexa Fluor 647Alexa Fluor 647標記的驢抗人IgG
xy-0297xy-xyE-xyy5.5    Donkey Anti-human IgG/PE-Cy5.5PE-Cy5.5標記的驢抗人IgG
xy-0297xy-xyE-xyy7    Donkey Anti-human IgG/PE-Cy7PE-Cy7標記的驢抗人IgG
xy-0297xy-xyy3    Donkey Anti-human IgG/Cy3Cy3標記的驢抗人IgG
xy-0297xy-xyy5    Donkey Anti-human IgG/Cy5Cy5標記的驢抗人IgG
xy-0297xy-xyy5.5    Donkey Anti-human IgG/Cy5.5Cy5.5標記的驢抗人IgG
xy-0297xy-xyy7    Donkey Anti-human IgG/Cy7Cy7標記的驢抗人IgG
xy-0297xy-xyE    Donkey Anti-human IgG/PEPE標記的驢抗人IgG