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轉(zhuǎn)運(yùn)蛋白2抗體

英文名稱 TNPO2
中文名稱 轉(zhuǎn)運(yùn)蛋白2抗體
別    名 Importin 3; IPO3; Karyopherin beta 2b, transportin; KPNB2B; TNPO2; Transportin 2 (importin 3, karyopherin beta 2b); Transportin 2 (Importin 3, karyopherin beta 2b), isoform CRA b; Transportin 2; TRN2.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Guinea Pig, Cat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60, 100kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNPO2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

產(chǎn)品介紹 background:
Protein transport across the nucleus is a selective, multi-step process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Two cytosolic factors centrally involved in the recognition and docking process are the karyopherin alpha 1 and karyopherin beta1 subunits. Karyopherin alpha 1 functions in the recognition and targeting of substrates destined for nuclear import, while karyopherin beta 1 serves as an adapter, tethering the karyopherin alpha 1/substrate complex to docking proteins on the nuclear envelope, termed nucleoporins. Karyopherin alpha 2 has been shown to complex with Epstein-Barr virus nuclear antigen 1 (EBNA-1). Karyopherin beta 2 and karyopherin beta 2B (also designated transportin 1 and transportin 2) share 84% sequence identity at the amino acid level, however, they have been shown to have different substrate specificities. Karyopherin beta 2 mediates hnRNPA1 nuclear import while karyopherin beta 2B has been implicated in the export of cellular mRNAs through complexes formed with the mRNA export factor TAP.

Function:
Transportin 2 (TNPO2) mediates nuclear import of HuR protein in vitro. It also participates in mRNA export from the nucleus.

Database links:

Entrez Gene: 30000 Human

Entrez Gene: 212999 Mouse

Entrez Gene: 304670 Ratxym-0297M-RBITxy    Mouse Anti-human IgG(3D3)/RBITC羅丹明標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-Golxy    Mouse Anti-human IgG(3D3)/Gold膠體金標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-FITxy    Mouse Anti-human IgG(3D3)/FITCFITC標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-Axy    Mouse Anti-human IgG(3D3)/AP堿性磷酸酶（AP）標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-xyE-xyy3    Mouse Anti-human IgG(3D3)/PE-Cy3PE-Cy3標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-xyE-xyY5    Mouse Anti-human IgG(3D3)/PE-CY5PE-CY5標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-Axyxy    Mouse Anti-human IgG(3D3)/APCAPC標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-AF350    Mouse Anti-human IgG(3D3)/Alexa Fluor 350Alexa Fluor 350標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-AF488    Mouse Anti-human IgG(3D3)/Alexa Fluor 488Alexa Fluor 488標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-AF555    Mouse Anti-human IgG(3D3)/Alexa Fluor 555Alexa Fluor 555標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-AF647    Mouse Anti-human IgG(3D3)/Alexa Fluor 647Alexa Fluor 647標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-xyE-xyy5.5    Mouse Anti-human IgG(3D3)/PE-Cy5.5PE-Cy5.5標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-xyE-xyy7    Mouse Anti-human IgG(3D3)/PE-Cy7PE-Cy7標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-xyy5.5    Mouse Anti-human IgG(3D3)/Cy5.5Cy5.5標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-xyy7    Mouse Anti-human IgG(3D3)/Cy7Cy7標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-xyy3    Mouse Anti-human IgG(3D3)/Cy3Cy3標(biāo)記的鼠抗人IgG單克隆抗體
xym-0297M-xyy5    Mouse Anti-human IgG(3D3)/Cy5Cy5標(biāo)記的鼠抗人IgG單克隆抗體
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xy-0292xy    BSA (bovine serum albumin)牛血清白蛋白（第五組分）
xyH-2    Protein G/FITCFITC標(biāo)記蛋白-G
xysl-xy8280    Cholesterol膽固醇
xy-0104xy    Beta-Amyloid(1-16)β淀粉樣肽1-16（多肽蛋白）
xy-0871xy    Beta-Amyloid (31-35)β淀粉樣肽31-35（多肽蛋白）
xy-0105xy    Beta-Amyloid(1-28)β淀粉樣肽1-28（多肽蛋白）
xy-0106xy    Beta-Amyloid(1-40)β淀粉樣肽（1-40）（多肽蛋白）
Y-0113    A Beta1-40 (mutation type, MT) peptide突變型β淀粉樣肽1-40
xy-0107xy    Beta-Amyloid (1-42)β淀粉樣肽（1-42）
xy-0057xy    Amylin糖尿病相關(guān)肽（胰島淀粉樣肽）
xy-0616xy    CCP peptide (cyclic citrullinated peptide,CCP)瓜氨酸環(huán)肽
xy-4536xy    Streptococcus suis 2 (Cell protein)2型豬鏈球菌菌體蛋白
xy-0038xy    GLP-1(Glucagon-like peptide-1)(7-36)peptide胰高血糖素樣肽-1（多肽）
xy-0995xy    ADM (Adrenomedullin)ProAM-N20 Rat, human, mo, pig, dog, bov腎上腺髓質(zhì)素蛋白(N端20肽)
xy-1158xy    AGEs晚期糖基化終末產(chǎn)物AGEs
xy-1158xyxy    AGEs control article(advanced glycosylation end products control article)晚期糖基化終末產(chǎn)物蛋白對照品
xy-0954xy    ET-1(Endothelin-1)內(nèi)皮素-1（蛋白多肽 活性蛋白）