環(huán)指蛋白88抗體 返回列表頁

環(huán)指蛋白88抗體

英文名稱 TRIM5 delta
中文名稱 環(huán)指蛋白88抗體
別    名 EG667823; Gm8833; RING finger protein 88; RNF88; TRIM5; Tripartite motif containing 5 transcript variant iota; Tripartite motif containing 5 transcript variant kappa; Tripartite motif containing protein 5; Tripartite motif protein 5; Tripartite motif protein TRIM5.

說 明 書 0.2ml  
研究領(lǐng)域 細胞生物  免疫學(xué)  環(huán)指蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM5 delta
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternay spliced isoforms, all of which lack a B-box type 1 domain, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. Additional domains C-terminal to the CC region are variably present. Expression of TRIM5 variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. The TRIM5 delta isoform has been shown to colocalize with the topoisomerase I-interacting proteins BTBD1 and BTBD2 in punctate or elongated cytoplasmic bodies in several mouse and human cells where it appears to serve as a scaffold for the assembly of endogenous BTBD proteins. TRIM5 delta also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner.

Subcellular Location:
Cytoplasmic bodies.

Database links:

Entrez Gene: 85363 Human

Entrez Gene: 319236 Mouse

Entrez Gene: 308906 Ratxy-13807R    CCDC62卷曲螺旋結(jié)構(gòu)域蛋白62抗體
xy-13808R    CCDC64卷曲螺旋結(jié)構(gòu)域蛋白64抗體
xy-13811R    CCDC72卷曲螺旋結(jié)構(gòu)域蛋白72抗體
xy-13812R    CCDC73卷曲螺旋結(jié)構(gòu)域蛋白73抗體
xy-13813R    CCDC74B卷曲螺旋結(jié)構(gòu)域蛋白74B抗體
xy-13782R    C19orf2519號染色體開放閱讀框25抗體
xy-13783R    C19orf4219號染色體開放閱讀框42抗體
xy-13784R    C19orf4419號染色體開放閱讀框44抗體
xy-13785R    C19orf4819號染色體開放閱讀框48抗體
xy-13786R    C19orf5019號染色體開放閱讀框50抗體
xy-13787R    C19orf5119號染色體開放閱讀框51抗體
xy-13788R    C19orf5219號染色體開放閱讀框52抗體
xy-13789R    C19orf5519號染色體開放閱讀框55抗體
xy-13790R    C19orf5619號染色體開放閱讀框56抗體
xy-13791R    C19orf5719號染色體開放閱讀框57抗體
xy-13792R    C19orf6119號染色體開放閱讀框61抗體
xy-13798R    C19orf7719號染色體開放閱讀框77抗體
xy-13800R    C1D核DNA結(jié)合蛋白C1D抗體
xy-13757R    C1orf1581號染色體開放閱讀框58抗體
xy-13758R    C21orf6621號染色體開放閱讀框66抗體
xy-13759R    CDC42EP3CDC42效應(yīng)蛋白3抗體
xy-15268R    C7orf 437號染色體開放閱讀框43抗體
xy-10351R    phospho-c-ABL (Tyr115)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10356R    phospho-c-Abl (Thr754 + Thr735) 磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10355R    phospho-c-ABL (Tyr245)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10354R    phospho-c-ABL(Thr413) 磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10353R    phospho-c-ABL(Tyr204)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10352R    phospho-c-ABL (Thr754)磷酸化非受體酪氨酸激酶c-Abl抗體
xy-10309R    Cenexin1精子尾部結(jié)構(gòu)蛋白抗體
xy-15198R    C5orf19 5號染色體開放閱讀框19抗體
xy-15313R    C9orf1399號染色體開放閱讀框139抗體
xy-15314R    C9orf1409號染色體開放閱讀框140抗體
xy-15315R    C9orf1429號染色體開放閱讀框142抗體
xy-15317R    C9orf1639號染色體開放閱讀框163抗體
xy-15318R    C9orf1699號染色體開放閱讀框169抗體
xy-15321R    C9orf173 9號染色體開放閱讀框173抗體
xy-15322R    C9orf219號染色體開放閱讀框21抗體
xy-10225R    phospho-CK II beta (Ser209)磷酸化絲氨酸/蘇氨酸蛋白激酶II β/casein kinase IIβ抗體