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TRMT1蛋白抗體

英文名稱(chēng) TRMT1
中文名稱(chēng) TRMT1蛋白抗體
別    名 TRM1; 2)G26)dimethyltransferase; 2-dimethylguanosine-26 methyltransferase; FLJ20244; N(2) N(2) dimethylguanosine tRNA methyltransferase; N(2)-N(2)) methyltransferase; TRM 1; TRM1 tRNA methyltransferase 1 homolog; TRM1_HUMAN; TRMT 1; Trmt1; tRNA (guanine(26)-N(2))-dimethyltransferase; tRNA 2 2 dimethylguanosine 26 methyltransferase; tRNA 2; tRNA(guanine 26 N(2) N(2)) methyltransferase; tRNA(guanine-26; tRNA(m(2 2)G26)dimethyltransferase; tRNA(m(2.
   
說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 72kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRMT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Transfer RNA (tRNA) modifications help regulate the efficiency of mRNA translation by maintaining the correct reading frames. N(2),N(2)-dimethylguanosine tRNA methyltransferase, also known as TRMT1 or tRNA(guanine-26,N(2)-N(2)) methyltransferase, is a 659 amino acid enzyme that is responsible for tRNA modifications in eukaryotes. Using S-adenosyl-L-methionine as a methyl donor, TRMT1 dimethylates a single guanine residue at position 26 of tRNA. TRMT1, which was initially identified in yeast and C. elegans, has a 26% and 31% sequence identity to its yeast and C. elegans homologs, respectively. There are two isoforms of TRMT1 produced by alternative splicing events. The TRMT1 gene maps to chromosome 19p13.13 and mutations in this gene lead to abrogated enzyme activity and a decrease in protein levels.

Function:
Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

Similarity:
Contains 1 C3H1-type zinc finger.

Gene ID:
55621

Database links:

Entrez Gene: 55621 Human

Entrez Gene: 212528 Mousexy-5823R    K Cadherin鈣粘蛋白6抗體
xy-5824R    Cadherin like 23鈣粘蛋白23抗體
xy-6296R    CDR2小腦變性相關(guān)蛋白2抗體
xy-6268R    CRK7細(xì)胞分裂周期2相關(guān)蛋白激酶7抗體
xy-2273R    CPa(Clostridium perfringens alpha toxin)A型產(chǎn)氣莢膜梭菌(魏氏梭菌)
xy-5404R    phospho-CK18(Ser34)磷酸化細(xì)胞角蛋白18抗體
xy-2950R    Cytosine deaminase胞嘧啶脫氨酶抗體
xy-15145R    C2GNT3C2GNT3蛋白抗體
xy-5460R    phospho-c-Jun(Thr239)磷酸化原癌基因c-Jun抗體
xy-5462R    phospho-c-Jun(Thr249)磷酸化原癌基因c-Jun抗體
xy-15590R    CYFRA21-1 腫瘤標(biāo)志物CYFRA21-1抗體
xy-5458R    phospho-c-Jun(Thr91)磷酸化原癌基因c-Jun抗體
xy-5739R    Cyclin A1周期素A1蛋白抗體
xy-5743R    CDKN3細(xì)胞周期蛋白依賴(lài)性激酶抑制蛋白3抗體
xy-11187R    CK42細(xì)胞角蛋白42
xy-4609R    CD105CD105抗體
xy-2322R    Caspase-7半胱胺酸蛋白酶蛋白-7抗體
xy-4602R    CD8CD8/CD8-β抗體
xy-5744R    CABLES2細(xì)胞周期蛋白依賴(lài)性激酶CABLES2抗體
xy-0432R    Chicken IgY兔抗雞IgY抗體
xy-15122R    C20orf12820號(hào)染色體開(kāi)放閱讀框128抗體
xy-4562R    CYP2E1細(xì)胞色素P450ⅡE1抗體
xy-4509R    CXCL13/BCA1B-淋巴細(xì)胞趨化因子抗體
xy-5740R    Cdc23細(xì)胞分裂周期蛋白23抗體
xy-5738R    CKAP5結(jié)腸和肝腫瘤高表達(dá)蛋白抗體
xy-5745R    CKS1細(xì)胞周期蛋白依賴(lài)性激酶調(diào)節(jié)亞基1抗體
xy-4614R    ICAM1細(xì)胞間粘附分子-1抗體
xy-4615R    ICAM1細(xì)胞間粘附分子1抗體
xy-4616R    ICAM1細(xì)胞間粘附分子-1抗體
xy-4617R    ICAM1細(xì)胞間粘附分子-1抗體
xy-4618R    ICAM1細(xì)胞間粘附分子-1抗體
xy-7624R    Cyclophilin F親環(huán)蛋白（親環(huán)素）PPIF抗體
xy-6874R    Catalase過(guò)氧化氫酶抗體
xy-7098R    CLIC4細(xì)胞內(nèi)氯離子通道蛋白4抗體
xy-6373R    CGR19細(xì)胞生長(zhǎng)調(diào)控蛋白19/環(huán)指蛋白197抗體
xy-7102R    CCDC139卷曲螺旋結(jié)構(gòu)域蛋白139抗體
xy-6375R    CHMP1A染色體修飾蛋白1抗體（金屬蛋白酶1）
xy-11812R    CAPS1鈣依賴(lài)分泌激活蛋白1抗體
xy-11814R    CBLN1小腦肽1抗體