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TRIM37蛋白抗體

英文名稱 TRIM37
中文名稱 TRIM37蛋白抗體
別    名 E3 ubiquitin protein ligase TRIM37; E3 ubiquitin-protein ligase TRIM37; KIAA0898; MUL; MUL protein; Mulibrey nanism gene; Mulibrey nanism protein; POB 1; POB1; RING B box coiled coil protein; TEF 3; TEF3; TRI37_HUMAN; TRIM 37; Trim37; Tripartite motif containing 37; Tripartite motif containing 37 protein; Tripartite motif containing protein 37; Tripartite motif-containing protein 37.
   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 108kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM37
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
TRIM37 is a protein that localizes to peroxisomes and contains a tripartite motif (TRIM) and a tumor necrosis factor-receptor associated factor (TRAF) domain. The protein and gene forms of TRIM37 are highly conserved between human and mouse. TRIM37 is expressed at a low level in the liver, ovary, heart, lung, skeletal muscle, and kidney, while it is highly expressed in the testis and brain, where it may act as an E3 ubiquitin ligase. Mutations in the TRIM37 gene result in Mulibrey nanism, an autosomal recessive prenatal-onset growth disorder that causes characteristic dysmorphic craniofacial features, heart disease, cardiopathy, failure of sexual maturation, and hepatomegaly.

Function:
E3 ubiquitin-protein ligase.

Subcellular Location:
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