跨膜蛋白16C抗體 返回列表頁

跨膜蛋白16C抗體

英文名稱 TMEM16C
中文名稱 跨膜蛋白16C抗體
別    名 Anoctamin 3; ANO3; C11orf25; GENX 3947; TMEM16C; Transmembrane protein 16C (eight membrane spanning domains); Transmembrane protein 16C; ANO3_HUMAN; DYT23; DYT24; GENX-3947.
   
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  新陳代謝  跨膜蛋白  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 115kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TMEM16C/Anoctamin 3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
TMEM16C is a 981 amino acid multi-pass membrane protein that is encoded by a gene which maps to chromosome 11. With approximay 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-angiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Function:
Anoctamin 3 belongs to the anoctamin family. Anoctamin 3 may act as a calcium activated chloride channel.

Subcellular Location:
Membrane; Multi pass membrane protein.

Similarity:
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xy-9555R    GLT8D1糖基轉(zhuǎn)移酶8結(jié)構(gòu)域1抗體
xy-9432R    RNF27環(huán)指蛋白27抗體
xy-11263R    GC1q R透明質(zhì)酸結(jié)合蛋白1抗體
xy-11235R    GRK6G蛋白偶聯(lián)受體激酶6抗體
xy-11248R    GRAF1 Rho GTP酶激活蛋白26抗體
xy-8556R    G Protein alpha Inhibitor 1G蛋白α抑制蛋白1抗體
xy-7549R    GAS 6生長停滯特異性蛋白6抗體
xy-11850R    Glutathione Synthetase谷胱甘肽合成酶抗體
xy-7635R    GYPB血型糖蛋白δ抗體
xy-6838R    GilZ糖皮質(zhì)激素誘導(dǎo)亮氨酸拉鏈蛋白抗體
xy-9909R    GGT6γ-谷氨酰轉(zhuǎn)肽酶6抗體
xy-12077R    GABRDG氨基丁酸受體δ/GABAA Rδ抗體
xy-12078R    GABRG1G氨基丁酸受體γ1/GABAA Rγ1抗體
xy-12079R    phospho-GABRG2(Ser366)磷酸化γ氨基丁酸γ2受體抗體
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xy-12081R    GABAREG氨基丁酸受體ε/GABAA Rε抗體