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腫瘤壞死因子C/淋巴毒素β抗體

英文名稱(chēng) Lymphotoxin Beta
中文名稱(chēng) 腫瘤壞死因子C/淋巴毒素β抗體
別    名 LT beta; LT-beta; LTB; lymphotoxin beta (TNF superfamily, member 3); lymphotoxin beta; lymphotoxin-beta; OTTHUMP00000038214; p33; TNF C; TNF-C; TNFC; TNFC_HUMAN; TNFSF3; tumor necrosis factor C (lymphotoxin beta); tumor necrosis factor C; tumor necrosis factor ligand superfamily member 3.

說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 腫瘤  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  細(xì)胞因子  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Lymphotoxin Beta
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex and this complex is the primary ligand for the lymphotoxin-beta receptor. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is probably non-functional. Alternative splicing results in multiple transcript variants encoding different isoforms. 

Function:
Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.

Subunit:
Heterotrimer of either two LTB and one LTA subunits or (less prevalent) one LTB and two LTA subunits.

Subcellular Location:
Membrane; Single-pass type II membrane protein (Potential).xy-13530R    GPR31G蛋白偶聯(lián)受體31抗體
xy-13531R    GPR32G蛋白偶聯(lián)受體32抗體
xy-13532R    GPR34G蛋白偶聯(lián)受體34抗體
xy-13533R    GPR35G蛋白偶聯(lián)受體35抗體
xy-13534R    GPR37G蛋白偶聯(lián)受體37/帕金森相關(guān)內(nèi)皮素受體樣受體抗體
xy-13535R    GPR40G蛋白偶聯(lián)受體40抗體
xy-13536R    GPR43G蛋白偶聯(lián)受體43抗體
xy-13537R    GPR44G蛋白偶聯(lián)受體44抗體
xy-13538R    GPR45G蛋白偶聯(lián)受體45抗體
xy-12352R    GSC同源盒蛋白GSC抗體
xy-13328R    Gemin 4脊髓性肌萎縮癥蛋白Gemin4抗體
xy-13329R    Gemin 5脊髓性肌萎縮癥蛋白Gemin5抗體
xy-13330R    Gemin 7脊髓性肌萎縮癥蛋白Gemin7抗體
xy-13331R    GEMGTP結(jié)合絲裂原誘導(dǎo)T細(xì)胞蛋白抗體
xy-13332R    GEMC1染色體卷曲螺旋域包含蛋白1抗體
xy-13333R    Gemin 6脊髓性肌萎縮癥蛋白Gemin6抗體
xy-13336R    phospho-GFAP (Ser38)磷酸化膠質(zhì)纖維酸性蛋白抗體
xy-13337R    GFI1自主生長(zhǎng)因子GFI1抗體
xy-10079R    GPR109AG蛋白偶聯(lián)受體109A抗體
xy-13343R    GGA1γ-銜接蛋白相關(guān)蛋白1抗體
xy-13344R    GGA2γ-銜接蛋白相關(guān)蛋白2抗體
xy-13345R    GGA3γ-銜接蛋白相關(guān)蛋白3抗體
xy-13347R    GGN配子生成素抗體
xy-13348R    GGT2 heavy chainγ谷氨酰轉(zhuǎn)肽酶2重鏈抗體
xy-13349R    GGT5 heavy chainγ-谷氨酰轉(zhuǎn)肽酶5重鏈抗體
xy-10279R    phospho-GATA3 (Ser115)磷酸化GATA結(jié)合蛋白3抗體
xy-10280R    phospho-GATA3 (Ser162)磷酸化GATA結(jié)合蛋白3抗體
xy-13339R    GFM2延伸因子G2抗體
xy-13383R    Glucoamylase葡糖淀粉酶抗體
xy-13341R    GFPT1谷氨酰胺6-磷酸果糖轉(zhuǎn)移酶抗體
xy-13400R    GSTT1谷胱甘肽S轉(zhuǎn)移酶θ抗體
xy-13441R    GSTT2谷胱甘肽S轉(zhuǎn)移酶θ2抗體
xy-13350R    GGT6γ-谷氨酰轉(zhuǎn)肽酶6抗體