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緊密連接蛋白2抗體

英文名稱 TJP2
中文名稱 緊密連接蛋白2抗體
別    名 Friedreich ataxia region gene X104 (tight junction protein ZO-2); MGC26306; Tight junction protein 2; Tight junction protein ZO 2; Tight junction protein ZO-2; TJP2; X104; ZO 2; ZO-2; ZO2; ZO2_HUMAN; Zona occludens protein 2; Zonula occludens protein 2
 
說 明 書 0.2ml  
研究領域
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, Guinea Pig, Danio rerio
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 131kDa
細胞定位 細胞核 細胞漿 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TJP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].

Function:
Plays a role in tight junctions and adherens junctions

Subunit:
Homodimer, and heterodimer with ZO1. Interacts with occludin, SAFB and UBN1. Interaction with SAFB occurs in the nucleus. Interacts with SCRIB.xy-2578R    GZMA/Granzyme A顆粒酶A抗體
xy-2579R    Granzyme D/B/E/N/G/F/H顆粒酶D/B/E/N/G/F/H抗體
xy-2574R    G-CSFR/CD114/GCSF Receptor粒細胞-巨噬細胞集落刺激因子3受體抗體
xy-2575R    GPA/GYPA/CD235a血型糖蛋白A/涎糖蛋白抗體
xy-13500R    GPATCH3G蛋白修補結構域蛋白3抗體
xy-15362R    GPR63G蛋白偶聯(lián)受體GPR63蛋白抗體
xy-4525R    phospho-GATA1(Ser161)磷酸化珠蛋白轉錄因子1抗體
xy-2582R    GPR109AG蛋白偶聯(lián)受體109A抗體
xy-3699R    GPR15G蛋白偶聯(lián)受體15抗體
xy-3689R    IL3RB粒細胞-巨噬細胞集落刺激因子受體β抗體
xy-6009R    GAS8生長停滯特異性蛋白8抗體
xy-15377R    GPR135G蛋白偶聯(lián)受體GPR135蛋白抗體
xy-2176R    Glypican 5磷脂?；嫉鞍拙厶?5抗體
xy-6008R    GADD45GIP1GADD45γ相互作用蛋白1抗體
xy-6010R    GTPBP4GTP結合蛋白4抗體（慢性腎功能衰竭蛋白）
xy-5358R    phospho-GABBR1 (Ser923)磷酸化gamma氨基丁酸B型受體1抗體
xy-5359R    phospho-Gria2 (Ser880)磷酸化谷氨酸受體2抗體
xy-5366R    phospho-GNA12(Ser68)磷酸化鳥苷酸調節(jié)蛋白12抗體
xy-3872R    GATA-1珠蛋白轉錄因子1抗體
xy-3883R    GPX3谷胱甘肽過氧化酶3
xy-3884R    GPX4谷胱甘肽過氧化酶4抗體
xy-4149R    GOLPH2高爾基體膜蛋白GP73抗體
xy-6151R    GPR172BG蛋白偶聯(lián)受體172B抗體
xy-6536R    GCET2生發(fā)中心B淋巴細胞相關蛋白2抗體
xy-6149R    GNAT3G蛋白轉錄因子α3抗體
xy-6150R    GPR124G蛋白偶聯(lián)受體124抗體（腫瘤血管內皮標記物）
xy-6594R    Galectin 1半乳糖凝集素1抗體
xy-6720R    GANABα葡萄糖苷酶2抗體
xy-5809R    Galectin 7半乳糖凝集素7抗體
xy-5886R    GCDFP15特異性囊腫病液體蛋白15抗體
xy-5932R    GCET1B淋巴細胞生發(fā)中心相關蛋白抗體
xy-5934R    GASC1鱗狀細胞癌增強蛋白1抗體