味覺受體蛋白家族2亞基60抗體 返回列表頁

味覺受體蛋白家族2亞基60抗體

英文名稱 T2R60
中文名稱 味覺受體蛋白家族2亞基60抗體
別    名 T2R56; TAS2R60; Taste receptor type 2 member 60; T2R60_HUMAN.

說 明 書 0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human T2R60
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
T2R60 is a 318 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. T2R60 acts as a receptor that may play a role in the perception of bitterness, and is also thought to be involved in sensing the chemical composition of gastrointestinal content. As a gustducin-linked receptor, the activity of T2R60 may stimulate G alpha (alpha gustducin), mediate PLC beta 2 activation and lead to the gating of TRPM5. While expressed in subsets of taste receptor cells of the tongue and palate epithelium, T2R60 is found exclusively in gustducin-positive cells. The gene that encodes T2R60 contains 957 bases and maps to human chromosome 7q35. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Function:
T2R60 may play a role in the perception of bitterness and is gustducin-linked. It is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. 

Subcellular Location:
Cell Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

Similarity:
Belongs to the G-protein coupled receptor T2R family. xy-11271R    HSPABP/HIP/HSC70 Interacting Protein HIP熱休克蛋白70相互作用蛋白抗體
xy-11277R    DNAJA1熱休克蛋白相關(guān)蛋白4抗體
xy-11290R    HAS2透明質(zhì)酸合成酶2抗體
xy-11292R    HOXA3同源盒基因HOXA3蛋白抗體
xy-11293R    HOXA4同源盒基因HOXA4蛋白抗體
xy-11294R    HOXA6同源盒基因HOXA6蛋白抗體
xy-11295R    HOXA7同源盒基因HOXA7蛋白抗體
xy-11296R    HSD17B4羥基類固醇(17β)脫氫酶4/17β-HSD4抗體
xy-9883R    HBZ血紅蛋白ζ鏈/Hemoglobin ζ 抗體
xy-9887R    HEBP1血紅素結(jié)合蛋白1抗體
xy-9889R    Hemoglobin alpha血紅蛋白α抗體
xy-9888R    Haptoglobulin beta結(jié)合球蛋白β抗體
xy-8042R    HIAT1海馬豐富基因轉(zhuǎn)錄蛋白1抗體
xy-8154R    Histone H2A.Z組蛋白H2AZ抗體
xy-15437R    HSF2 binding protein熱休克因子2結(jié)合蛋白抗體
xy-8041R    HEATR2HEATR2蛋白抗體
xy-15417R    HBLD2鐵硫簇整合同源物2蛋白抗體
xy-0887R    MV hemagglutinin glycoprotein麻疹病毒血凝素抗體
xy-11589R    HOXC5同源盒蛋白HOXC5抗體
xy-11567R    HES4轉(zhuǎn)錄因子HES4抗體
xy-11568R    HS1BP3造血干細(xì)胞特異性相關(guān)結(jié)合蛋白3抗體
xy-8316R    HDHD1HDHD1蛋白抗體
xy-8317R    HDHD2HDHD2蛋白抗體
xy-7803R    HCF-1宿主細(xì)胞因子1抗體
xy-7749R    HIST1H2AH組蛋白H2A/S抗體
xy-6664R    HRH2組胺受體H2抗體
xy-6665R    phospho-HRH1(Ser398)磷酸化組胺受體H1抗體
xy-6666R    HOXA11同源盒蛋白HOXA11抗體
xy-6663R    HRH1組胺受體H1抗體
xy-6667R    HOXA9同源盒蛋白HOXA9抗體
xy-6668R    HOXB5同源盒蛋白HOXB5抗體
xy-5840R    HEPACAM肝細(xì)胞粘附分子抗體
xy-10326R    Phospho-HDAC5 (Ser259)磷酸化組蛋白去乙?；?抗體