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細(xì)胞骨架結(jié)合蛋白2抗體

英文名稱 TWF2
中文名稱 細(xì)胞骨架結(jié)合蛋白2抗體
別    名 A6 related protein; A6r; A6RP; hA6RP; MSTP011; Protein tyrosine kinase 9 like; PTK 9L; PTK9L; PTK9L; PTK9L protein tyrosine kinase 9 like; TWF 2; Twinfilin 1 like protein; Twinfilin 2; Twinfilin actin binding protein homolog 2; Twinfilin like protein; Twinfilin2; TWF2_HUMAN.
  
說(shuō) 明 書 0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  結(jié)合蛋白  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TWF2/PTK9L
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein. [provided by RefSeq, Jul 2008]

Function:
TWF2 (Twinfilin 2) was identified by its interaction with the catalytic domain of protein kinase C zeta. It contains an actin binding site and an ATP binding site and is most closely related to twinfilin (PTK9), a conserved actin monomer binding protein. TWF2 is an actin binding protein involved in motile and morphological processes. It inhibits actin polymerization, likely by sequestering G actin. By capping the barbed ends of filaments, it also regulates motility. It seems to play an important role in clathrin mediated endocytosis and distribution of endocytic organelles.

Subunit:
Interacts with G-actin; ADP-actin form and capping protein (CP). May also be able to interact with TWF1 and phosphoinositides, PI(4,5)P2. When bound to PI(4,5)P2, it is down-regulated. Interacts with MYO7A

Subcellular Location:
Cytoplasmic, cytoskeleton. Cytoplasmic, perinuclear region. Note: Perinuclear and G actin rich cortical actin structures sublocalization.xy-5388R    phospho-HDAC1 (Ser423+Ser421) 磷酸化組蛋白去乙?；?抗體
xy-5389R    phospho-HDAC2 (Ser394)磷酸化組蛋白去乙酰化酶2抗體
xy-5392R    phospho-HOMER3 (Thr36)磷酸化HOMER3蛋白抗體
xy-6165R    HRAS+KRAS轉(zhuǎn)化蛋白p21抗體（原癌基因H-ras抗體）
xy-2972R    HES1轉(zhuǎn)錄因子HES-1抗體
xy-6191R    H3-K4-HMTase SETD7組蛋白H4-K4甲基轉(zhuǎn)移酶抗體
xy-5391R    HOMER3HOMER3蛋白抗體
xy-5340R    Phospho-HER3(Tyr1328)磷酸化HER3受體抗體
xy-5342R    Phospho-HER4 (Tyr1162)磷酸化HER4抗體
xy-5343R    Phospho-HER4 (Tyr1188)磷酸化HER4抗體
xy-3905R    HSD17B3羥類固醇脫氫酶17β3抗體
xy-3904R    HSD11B1羥基類固醇脫氫酶11β1抗體
xy-3906R    HSD3B1滋養(yǎng)層細(xì)胞抗原3β-HSD抗體
xy-4016R    Acetyl-Histone H4(K8)乙?；M蛋白H4抗體
xy-5384R    phospho-HMGN1(Ser20+Ser24)磷酸化高遷移率核小體結(jié)合蛋白1
xy-4838R    HE4附睪分泌蛋白4抗體
xy-4715R    Histone H3 (Tri Methyl K4)*基化組蛋白H3抗體
xy-5068R    HMGCR三羥基*基輔酶A還原酶抗體
xy-5072R    Heparan Sulfate Proteoglycan 2硫酸乙酰肝素蛋白多糖2
xy-15421R    HCA25a肝癌相關(guān)抗原h(huán)ca25a
xy-3994R    Hexokinase 3己糖激酶3抗體
xy-2327R    HBV pre S1 protein人乙肝病毒pre S1/S2蛋白抗體
xy-2328R    HBV pre S1 protein人乙肝病毒pre S1蛋白抗體
xy-3992R    Hexokinase 1己糖激酶1抗體
xy-3993R    Hexokinase 2己糖激酶2抗體
xy-10100R    HSP90 alpha熱休克蛋白90α抗體
xy-6894R    HFREP1肝細(xì)胞源性纖維蛋白原相關(guān)蛋白1抗體
xy-12303R    Hemogen紅細(xì)胞分化相關(guān)基因蛋白抗體
xy-12244R    HOXA13同源異型盒基因HOXA13抗體
xy-10325R    Phospho-HDAC4 (Ser246)磷酸化組蛋白去乙酰化酶4(Ser246)抗體
xy-10327R    Phospho-HDAC7(Ser155)磷酸化組蛋白去乙?；?抗體
xy-10328R    phospho-HDAC4 (Ser632)磷酸化組蛋白去乙酰化酶4抗體
xy-10330R    phospho-HDAC7(Ser486)磷酸化組蛋白去乙?；?抗體
xy-12269R    HIRIP3HIRA相互作用蛋白3抗體
xy-12287R    HOOK1HOOK1蛋白抗體
xy-10481R    HIV2 gp41 + gp160人類免疫缺陷病毒2型/2型艾滋病病毒gp41+gp160抗體
xy-10482R    HIV2 gp120 + gp160人類免疫缺陷病毒2型/2型艾滋病病毒gp41+gp160抗體
xy-13610R    HCG3HCG3蛋白抗體