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跨膜蛋白132A抗體

英文名稱 TMEM132A
中文名稱 跨膜蛋白132A抗體
別    名 GBP; HSPA5-binding protein 1; HSPA5BP1; T132A_HUMAN; Tmem132a; Transmembrane protein 132A.
   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 神經(jīng)生物學(xué)  細(xì)胞凋亡  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 106kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TMEM132A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
TMEM132A is a 560 amino acid protein encoded by a gene mapping to human chromosome 11. With approximay 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-angiectasia. The blood disorders Sickle cell anemia and ∫ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Function:
May play a role in embryonic and postnatal development of the brain. Increased resistance to cell death induced by serum starvation in cultured cells. Regulates cAMP-induced GFAP gene expression via STAT3 phosphorylation.

Subunit:
Interacts with HSPA5/GRP78 xy-8505R    hnRNP M異質(zhì)性核糖核蛋白M抗體
xy-4626R    HE4附睪分泌蛋白4抗體
xy-15416R    HBLD1鐵硫簇整合同源物2蛋白抗體
xy-15491R    HIGD2AHIG1區(qū)域家族成員2A抗體
xy-1808R    Hpt/Haptoglobin結(jié)合珠蛋白/觸珠蛋白抗體
xy-1820R    HMGB4高遷移率族蛋白B4抗體
xy-1904R    Syndecan 2/heparin sulphate protoglycans 1硫酸肝素糖蛋白1抗體抗體
xy-1775R    HFH-4叉頭蛋白J1抗體
xy-4981R    HIV p55+NP7艾滋病病毒抗體
xy-4980R    HIV p55+P6-Gag艾滋病病毒抗體
xy-4982R    HIV1 p55+p17艾滋病病毒抗體
xy-9912R    HPR結(jié)合珠蛋白相關(guān)蛋白抗體
xy-1054R    HDCL-組氨酸脫羧酶抗體
xy-6869R    HBXIP乙型肝炎病毒X蛋白相互作用蛋白
xy-13543R    Histone H2B.s組蛋白H2B.s抗體
xy-12156R    HDAC4 + 5 + 9組蛋白去乙?；?+5+9抗體
xy-6986R    HSPBAP1熱休克蛋白27相關(guān)蛋白1抗體
xy-9068R    HMBS卟膽原脫氨酶抗體
xy-9071R    HORMAD2異質(zhì)核糖核蛋白U2樣蛋白抗體
xy-9072R    HRP2肝癌衍生生長因子2抗體
xy-7645R    HCA57肝癌相關(guān)抗原57抗體
xy-0367G    Complement C3補(bǔ)體C3抗體
xy-2004R    H1N1 Hemagglutinin 2甲型流感病毒血凝素抗體
xy-1597R    HRPT2甲狀旁腺功能亢進(jìn)蛋白2/細(xì)胞分裂周期73抗體
xy-1271R    HTRA2線粒體絲氨酸蛋白酶抗體
xy-9858R    HCN2鉀/鈉超極化激活環(huán)核苷酸門控通道蛋白2抗體
xy-9854R    HSPβ7熱休克蛋白β7抗體
xy-9856R    HCN3鉀/鈉超極化激活環(huán)核苷酸門控通道蛋白3抗體
xy-6372R    Hepcidin-25鐵調(diào)節(jié)蛋白25抗體
xy-15431R    HDDC2HD域內(nèi)含蛋白2抗體
xy-9841R    HIV1 p55 + p17艾滋病病毒p55抗體
xy-1438R    Hck造血細(xì)胞激酶抗體
xy-15441R    HEATR5BHEAT重復(fù)內(nèi)含蛋白5B蛋白抗體
xy-15489R    HIGD1B缺氧誘導(dǎo)基因1B蛋白抗體
xy-4706R    Acetyl-Histone H4(K5)乙?；M蛋白H4抗體
xy-4782R    HSPB2熱休克蛋白B2抗體
xy-8604R    HLA B27人類白細(xì)胞抗原B27
xy-11937R    Protein atonal homolog 8螺旋環(huán)螺旋轉(zhuǎn)錄因子HATH6抗體