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谷氨酰胺轉(zhuǎn)胺酶2抗體

英文名稱 Transglutaminase 2
中文名稱 谷氨酰胺轉(zhuǎn)胺酶2抗體
別    名 TG 2; TG(C); TG2; TGase C; TGase H; TGase-2; TGase2; TgaseII; ALPHA SUBUNIT; C polypeptide; G alpha h; G protein alpha subunit Gh class; G[a]h; Gh CLASS G ALPHA h; GNAH; GNAH G PROTEIN; Guanine nucleotide binding protein H polypeptide; H POLYPEPTIDE; Protein glutamine gamma glutamyltransferase 2; Protein glutamine gamma glutamyltransferase; Protein-glutamine gamma-glutamyltransferase 2; TGC; TGC GUANINE NUCLEOTIDE BINDING PROTEIN; TGM 2; TGM2; TGM2_HUMAN; Tissue transglutaminase; Tissue type transglutaminase; Transglutaminase 2; Transglutaminase 2 C polypeptide; Transglutaminase C; Transglutaminase H; Transglutaminase-2; tTG; tTGas.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細胞生物  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Transglutaminase 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. Human keratinocyte transglutaminase (TGase1) is a membrane associated, 817 amino acid protein. Human tissue transglutaminase (TGase2) is an endothelial cell specific, 687 amino acid protein.

Function:
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.

Subunit:
Monomer. xy-10069R    IL-31白細胞介素31抗體
xy-0474R    human Serum IgA人血清型免疫球蛋白A抗體
xy-7867R    Iroquois homeobox protein 3Irx3蛋白抗體
xy-7866R    Intra Acrosomal Protein精子頂端體蛋白10抗體
xy-4964R    human secretory IgA人分泌型免疫球蛋白A
xy-11349R    ICA1胰島細胞自身抗原1抗體
xy-11321R    Islet 2胰島素基因增強結(jié)合蛋白2抗體
xy-0768R    IL-16白介素-16抗體
xy-1363R    AIF1離子鈣接頭蛋白抗體
xy-9464R    IRX4Iroquois同源蛋白4抗體
xy-6877R    IFRD1干擾素相關(guān)發(fā)育調(diào)節(jié)蛋白1抗體（神經(jīng)生長因子誘導蛋白PC4）
xy-6870R    ILP2抑制細胞凋亡樣蛋白2抗體
xy-4750R    IFITM1干擾素誘導跨膜蛋白1抗體
xy-8690R    IFI44干擾素誘導蛋白44抗體
xy-6471R    ITPR35-三磷酸肌醇受體3抗體
xy-15525R    IFNW1干擾素omega 1蛋白抗體
xy-15521R    IFNA7干擾素alpha 7蛋白抗體
xy-0787R    IFN-Beta干擾素β抗體
xy-3529R    ID1DNA結(jié)合抑制因子1抗體
xy-8676R    IFI-202γ干擾素誘導蛋白202抗體
xy-0788R    intestinal FABP/IFABP/FABP2腸型脂肪酸結(jié)合蛋白抗體
xy-1291R    ING1生長抑制因子基因1抗體
xy-0780R    IL-8/CXCL8白介素8抗體
xy-0317R    ILK-1整合素連接激酶-1抗體
xy-3235R    phospho-IKK alpha (Ser176 + Ser180)磷酸化KB抑制蛋白激酶α抗體
xy-3236R    Phospho-IKK alpha(Ser180) + IKK beta(Ser181)磷酸化KB抑制蛋白激酶α/β抗體
xy-3237R    Phospho-IKK alpha/beta (Ser176 + Ser180)磷酸化KB抑制蛋白激酶α/β抗體
xy-15563R    IFT46細胞纖毛內(nèi)轉(zhuǎn)運同源蛋白46抗體
xy-2459R    IL-10RA白細胞介素-10受體a抗體
xy-2460R    IL-13Ra1白細胞介素-13受體a1抗體