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胰蛋白酶抑制劑抗體

文名稱 Trypsin Inhibitor
中文名稱 胰蛋白酶抑制劑抗體
別    名 Peptidase inhibitor 15; PI-15; 25 kDa trypsin inhibitor; p25TI; Cysteine-rich secretory protein 8; CRISP-8; SugarCrisp; PI15_HUMAN.
  
說 明 書 0.2ml  
研究領(lǐng)域 細胞生物  免疫學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
細胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Trypsin Inhibitor
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-8 (Cysteine-rich secretory protein 8), also known as PI15 (Peptidase inhibitor 15), P25TI or SugarCrisp, is a 258 amino acid secreted protein that belongs to the CRISP family. Expressed at low levels in thyroid, prostate, salivary and mammary tissue, CRISP-8 functions as a serine protease inhibitor that exhibits weak inhibitory action against Trypsin, a serine protease found in the digestive system. In addition to its role as a protease inhibitor, CRISP-8 is secreted in neuroblastoma and glioblastoma cell lines, suggesting a role for CRISP-8 in tumor formation and metastasis within the central nervous system.

Function:
The soybean trypsin inhibitor was first crystallized by Kunitz in 1945 and is Serine protease inhibitor which displays weak inhibitory activity against trypsin. 

Subcellular Location:
Secreted.

Tissue Specificity:
Weakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland. 

Post-translational modifications:
N-glycosylated (Probable). xy-4015R    IRGM免疫相關(guān)鳥苷三磷酸酶基因抗體
xy-2461R    IL-13Ra2白細胞介素-13受體a2抗體
xy-2450R    I-309嗜酸粒細胞趨化蛋白CCL1抗體
xy-3226R    phospho-IGF1R (Tyr1161)磷酸化胰島素樣生長因子1受體抗體
xy-0018R    IDE胰島素降解酶抗體
xy-1789R    IL-12白介素12抗體
xy-1740R    IL-4白介素4抗體
xy-6059R    IGFBP9胰島素樣生長因子結(jié)合蛋白9抗體
xy-2710R    IFNGR2干擾素-gamma受體2抗體
xy-2711R    IL-27R白細胞介素27受體抗體
xy-2216R    IL-1RA白介素-1受體拮抗劑抗體
xy-2898R    IKK gammaKB抑制蛋白激酶γ抗體
xy-3227R    phospho-IKK gamma (Ser85)磷酸化KB抑制蛋白激酶γ抗體
xy-3228R    phospho-IKK gamma (Ser31)磷酸化KB抑制蛋白激酶γ抗體
xy-3229R    Phospho-IKK alpha (Thr23)磷酸化KB抑制蛋白激酶α/IKK α 抗體
xy-3232R    phospho-IKK beta(Tyr199)磷酸化KB抑制蛋白激酶β抗體
xy-3233R    phospho-IKK beta(Tyr188)磷酸化KB抑制蛋白激酶β抗體
xy-3234R    phospho-IKK alpha (Tyr463)磷酸化KB抑制蛋白激酶α抗體
xy-3230R    phospho-IKK gamma (Ser376)磷酸化KB抑制蛋白激酶γ抗體
xy-3231R    phospho-IKK beta(Ser466)磷酸化KB抑制蛋白激酶β抗體
xy-15552R    IFI6干擾素alpha誘導(dǎo)蛋白6抗體
xy-2613R    IL-17E/IL-25白介素-17E抗體
xy-2736R    phospho-IRS-1(Ser307)磷酸化胰島素受體底物p-IRS-1/2抗體
xy-15529R    IARS2tRNA異亮氨酸連接酶抗體
xy-10132R    Integrin alpha 2/CD49b整合素α2抗體
xy-15515R    IFIT3干擾素誘導(dǎo)的三角形四肽重復(fù)蛋白3抗體
xy-15516R    IFIT5干擾素誘導(dǎo)的三角形四肽重復(fù)蛋白5抗體
xy-15517R    IFITM2干擾素誘導(dǎo)跨膜蛋白2抗體
xy-15518R    IFITM5干擾素誘導(dǎo)跨膜蛋白5抗體
xy-15522R    phospho-IFNAR1（Tyr466) 干擾素alpha/beta 受體1蛋白抗體
xy-15523R    phospho-IFNGR1 (Tyr457)干擾素gamma受體1蛋白抗體
xy-15527R    IF3EI 真核翻譯起始因子3亞基L蛋白抗體