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轉錄因子12抗體

英文名稱 TCF12
中文名稱 轉錄因子12抗體
別    名 bHLHb20; Class B basic helix-loop-helix protein 20; DNA binding protein HTF4; DNA-binding protein HTF4; E box binding protein; E-box-binding protein; HEB; HTF4; HTF4_HUMAN; TCF-12; Tcf12; Transcription factor 12; Transcription factor HTF-4; Transcription factor HTF4.
    
說 明 書 0.2ml  
研究領域 轉錄調節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Horse, Rabbit, Zebrafish, Sheep, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 73kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TCF12
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes. Both homo- and hetero-oligomers of these proteins are able to distinguish very closely related E box proteins and are believed to play important roles in lineage specific gene expression.

Function:
Binds specifically to oligomers of E-box motifs. May play important roles during development of the nervous system as well as in other organ systems.

Subunit:
Contains 1 basic helix-loop-helix (bHLH) domain.

Subcellular Location:
Nucleus.xy-0529R    IL-18白細胞介素-18/干擾素γ誘導因子抗體
xy-0445R    IL1RAPL1白介素1受體相關蛋白樣1前體蛋白抗體
xy-0812R    IL-1 Beta白介素1β/IL-1β抗體
xy-1191R    IL-2白介素2抗體（大、小鼠）
xym-0389M    IL-2(H2E4)白細胞介素-2單克隆抗體
xy-1193R    IL-23白介素-23抗體
xy-0581R    IL-4白介素4抗體
xy-0781R    IL-6白介素6
xy-0782R    IL-6白介素6抗體
xy-0379R    IL-6白介素6抗體
xy-1032R    Inhibin Alpha抑制素A/Inhibin α抗體
xy-1674R    ILTV glycoprotein E雞傳染性喉氣管炎病毒糖蛋白E抗體
xy-0898R    intestinal FABP小腸型脂肪酸結合蛋白抗體
xy-1540R    IL-7Ra白細胞介素-7受體a抗體
xy-2093R    Integrin alpha 3整合素α3抗體
xy-2094R    Integrin beta 5整合素β5抗體
xy-2095R    Integrin alpha 1整合素α1抗體
xy-1959R    IL2 Receptor beta白介素2受體β鏈抗體 IL-2Rβ
xy-0536R    Interferon alpha 2b干擾素α2b抗體
xy-2471R    ICOS ligand誘導協(xié)同刺激分子配體CD275抗體
xy-10050R    IBDV雞傳染性法氏囊病病毒抗體
xy-2140R    IL-17白介素-17抗體
xy-5924R    IMPDH25'肌苷磷酸脫氫酶2抗體
xy-15545R    IER5L即刻早期應答基因5樣蛋白抗體
xy-2250R    CD51整合素αV抗體
xy-2618R    IL-19/NG.1白細胞介素-19抗體
xy-2598R    IL-3白介素3抗體
xy-2600R    IL-3R alpha/CD123白介素3受體a鏈抗體
xy-2601R    IL5RA/CD125白介素-5受體α鏈抗體IL-5Rα
xy-2602R    IL-10RB/CRFB4白細胞介素-10受體β抗體
xy-2603R    IL-12RB1/CD212白細胞介素-12受體β1抗體
xy-2604R    IL12RB2白細胞介素-12受體β2抗體