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動(dòng)力蛋白輕鏈

英文名稱 DYNLT1
中文名稱 動(dòng)力蛋白輕鏈
別    名 TC1; DYNLT1; Dynein light chain Tctex-type 1; Protein CW-1; T-complex testis-specific protein 1 homolog; DYLT1_HUMAN; TCTEX-1; TCTEX1.

說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  細(xì)胞外基質(zhì)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, 
產(chǎn)品應(yīng)用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TC1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產(chǎn)品介紹 background:
Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005 [PubMed 15992542]).[supplied by OMIM, Mar 2008]. 

Function:
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site. May also be a accessory component of axonemal dynein.
Plays a role in neuronal morhpogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagoxy-15549R    IFI27 alpha干擾素誘導(dǎo)蛋白27抗體
xy-15565R    IFT81細(xì)胞纖毛內(nèi)轉(zhuǎn)運(yùn)同源蛋白81抗體
xy-15548R    IFI16Gamma干擾素誘導(dǎo)蛋白16抗體
xy-15538R    IDH3B異檸檬酸脫氫酶3 beta亞基抗體
xy-15553R    IFIT1 干擾素誘導(dǎo)的三角形四肽重復(fù)蛋白1抗體
xy-15539R    IDH3G異檸檬酸脫氫酶gamma亞基抗體
xy-15541R    IDN3Bipped B樣蛋白抗體
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xy-15542R    IDUAα-L-艾杜糖苷酶抗體
xy-15558R    IFT122細(xì)胞纖毛內(nèi)轉(zhuǎn)運(yùn)同源蛋白122抗體
xy-15559R    IFT140細(xì)胞纖毛內(nèi)轉(zhuǎn)運(yùn)同源蛋白140抗體
xy-15561R    IFT20細(xì)胞纖毛內(nèi)轉(zhuǎn)運(yùn)同源蛋白20抗體
xy-15562R    IFT43細(xì)胞纖毛內(nèi)轉(zhuǎn)運(yùn)同源蛋白43抗體
xy-15564R    IFT80細(xì)胞纖毛內(nèi)轉(zhuǎn)運(yùn)同源蛋白80抗體
xy-9195R    CD101CD101抗體
xy-9197R    IGSF5免疫球蛋白超家族成員5抗體
xy-15550R    IFI27L2alpha干擾素誘導(dǎo)蛋白27樣蛋白2抗體
xy-0862R    Insulin胰島素抗體
xy-15526R    IER5
xy-15547R    IFFO2中間絲家族孤啡肽2蛋白抗體
xy-1448R    Jagged1CD339抗體
xy-3651R    JAM1連接粘附分子1抗體
xy-1393R    Jun D活化蛋白激酶D抗體
xy-1394R    Jab1Jun激活區(qū)域-連接蛋白1抗體
xy-3206R    phospho-JAK2(Tyr221)磷酸化蛋白酪氨酸激酶JAK-2抗體
xy-2808R    Jak3蛋白酪氨酸激酶JAK-3抗體
xy-3207R    Phospho-Jak3 (Tyr785)磷酸化蛋白酪氨酸激酶JAK-3抗體
xy-3208R    Phospho-Jak3 (Tyr980 + Tyr981)磷酸化蛋白酪氨酸激酶JAK-3抗體
xy-3209R    phospho-c-Jun(Thr93)磷酸化原癌基因c-Jun抗體
xy-0908R    JAK2蛋白質(zhì)酪氨酸激酶JAK2抗體
xy-9706R    JWAJWA蛋白抗體
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xy-11086R    JAMC連接粘附分子C抗體
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xy-8046R    JMJD2A組蛋白去甲基化酶JMJ2A抗體
xy-8047R    JMJD5組蛋白去甲基化酶JMJD5抗體
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