硫氧環(huán)蛋白還原酶1抗體 返回列表頁

硫氧環(huán)蛋白還原酶1抗體

英文名稱 TXNRD1
中文名稱 硫氧環(huán)蛋白還原酶1抗體
別    名 cytoplasmic; Gene associated with retinoic and IFN-induced mortality 12 protein; Gene associated with retinoic and interferon-induced mortality 12 protein; Gene associated with retinoid IFN induced mortality 12 protein; GRIM 12; GRIM-12; GRIM12; KDRF; KM 102 derived reductase like factor; KM-102-derived reductase-like factor; MGC9145; Oxidoreductase; Thioredoxin reductase 1; Thioredoxin reductase 1 cytoplasmic; Thioredoxin reductase GRIM 12 antibody Thioredoxin reductase TR1; TR 1; TR; TR1; TRXR 1; TRXR1; TRXR1_HUMAN; TXNR; TXNRD 1; Txnrd1.

說 明 書 0.2ml  
研究領域 細胞生物  免疫學  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TXNRD1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Subunit:
Homodimer. Isoform 4 interacts with ESR1 and ESR2. Interacts with HERC5.

Subcellular Location:
Cytoplasm. Isoform 4: Cytoplasm. Nucleus. Isoform 5: Cytoplasm.

Tissue Specificity:
Isoform 1 is expressed predominantly in Leydig cells (at protein level). Also expressed in ovary, spleen, heart, liver, kidney and pancreas and in a number of cancer cell lines. Isoform 4 is widely expressed with highest levels in kidney, testis, uterus, ovary, prostate, placenta and fetal liver.

Post-translational modifications:
The N-terminus of isoform 5 is blocked. 
ISGylated (Probable). xy-5847R    ADAM12去整合素樣金屬蛋白酶12抗體
xy-5848R    ADAM15去整合素樣金屬蛋白酶15抗體
xy-5851R    ADAM2去整合素樣金屬蛋白酶2抗體
xy-6651R    ApoER2載脂蛋白E2受體抗體
xy-6649R    ADORA1腺苷A1受體抗體
xy-6661R    AQP0水通道蛋白0抗體
xy-6694R    AP2 gamma轉錄因子AP-2γ抗體
xy-7046R    ANGPTL5血管生成素相關蛋白5
xy-6437R    ANKRD53錨蛋白重復域53抗體
xy-8309R    ANKRD54錨蛋白重復域54抗體
xy-8600R    ATP5BATP合成酶β5抗體
xy-11650R    ALS2CR3肌萎縮側索硬化癥相關蛋白3抗體
xy-10205R    ADORA2B腺苷A2b受體/神經(jīng)生長因子1受體抗體
xy-11649R    ALS2CR1肌萎縮側索硬化癥相關蛋白1抗體
xy-11651R    APBA2β淀粉樣前體蛋白結合蛋白2抗體（X11β）
xy-11658R    Diazepam Binding Inhibitor乙酰輔酶A結合蛋白抗體
xy-7833R    phospho-CDC16(Ser560)磷酸化細胞分裂周期蛋白16抗體
xy-7854R    AHI1白血病相關蛋白AHI1抗體
xy-7855R    AICDA活化誘導胞嘧啶核苷脫氨酶抗體
xy-7853R    ABCA9三磷酸腺苷結合盒轉運蛋白9抗體
xy-12509R    ARF3ADP核糖基化因子3抗體
xy-11389R    AARSD1含丙氨酰tRNA合成酶結構域1抗體
xy-11070R    AMIGO1粘附分子IgG樣結構域蛋白1抗體
xy-11053R    KAL1卡爾曼綜合癥基因1抗體
xy-9134R    ASB7含錨蛋白重復序列-細胞因子信號抑制物盒蛋白家族7抗體
xy-9135R    ASB17含錨蛋白重復序列-細胞因子信號抑制物盒蛋白家族17抗體
xy-9129R    ASB12含錨蛋白重復序列-細胞因子信號抑制物盒蛋白家族12抗體
xy-1152R    ATPase Na+/ K+ beta 2鈉鉀ATP酶通道蛋白抗體
xy-9095R    AGXT2L2AGXT2L2蛋白抗體
xy-9097R    ANKS1Bβ淀粉樣蛋白胞內結構域相關蛋白1抗體
xy-9099R    ANKS6錨蛋白重復及SAM結構域蛋白6抗體
xy-9103R    ART3二磷酸腺苷核糖基轉移酶3抗體