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TRIM50蛋白抗體

英文名稱 TRIM50
中文名稱 TRIM50蛋白抗體
別    名 E3 ubiquitin ligase; E3 ubiquitin protein ligase TRIM50; TRIM50A; Tripartite motif containing protein 50; tripartite motif protein 50A; tripartite motif-containing 50A; TRI50_HUMAN.

說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM50
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM50 (tripartite motif containing 50), also known as TRIM50A or E3 ubiquitin-protein ligase TRIM50, is a 487 amino acid cytoplasmic protein that functions as an E3 ubiquitin-protein ligase. Containing one RING-type zinc finger, a B30.2/SPRY domain and a single B box-type zinc finger, TRIM50 belongs to the TRIM/RBCC family and undergoes post-translational auto-ubiquitination. TRIM50 exists as two alternatively spliced isoforms, designated TRIM50 alpha and TRIM50 beta, and has the ability to form dimers and trimers. The gene encoding TRIM50 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Function:
E3 ubiquitin-protein ligase. xy-12571R    BANF1障礙自整合蛋白BAF抗體
xy-12553R    phospho-B MyB (Ser577 + Ser581)磷酸化轉(zhuǎn)錄因子MYB相關(guān)蛋白B抗體
xy-12554R    phospho-B MyB (Thr487)磷酸化轉(zhuǎn)錄因子MYB相關(guān)蛋白B抗體
xy-12555R    phospho-B-Raf (Ser729)磷酸化B-Raf抗體
xy-12556R    phospho-B Raf (Thr446 + Ser601)磷酸化B-Raf抗體
xy-12557R    phospho-B Raf (Thr598)磷酸化B-Raf抗體
xy-12558R    phospho-B Raf (Thr753)磷酸化B-Raf抗體
xy-12563R    BACH2轉(zhuǎn)錄調(diào)節(jié)蛋白BACH2抗體
xy-12564R    Bacillus anthracis lethal factor炭疽桿菌致死因子LF抗體
xy-12322R    Protein BOC蛋白BOC抗體
xy-12307R    BP1氨肽酶A抗體
xy-7132R    BNP腦鈉素/利鈉肽抗體
xy-15534R    Bcl-2 betaBcl2 beta蛋白抗體
xy-2668R    Bone sialoprotein骨涎蛋白抗體
xy-1488R    Bim細(xì)胞死亡調(diào)解子抗體
xy-1489R    BIRC6Apollon凋亡抑制蛋白抗體
xy-1628R    BONZO細(xì)胞表面趨化因子受體6抗體
xy-1195R    beta endorphinβ-內(nèi)啡肽/β endorphin抗體
xy-1509R    BMPR1A骨成型蛋白受體1A抗體
xy-1336R    Bcl-xLBcl-xL蛋白抗體
xy-1337R    phospho-Bcl-xL (Ser62)磷酸化Bcl-xL(Ser62)抗體
xy-1304R    Bad相關(guān)死亡促進(jìn)因子Bad抗體
xy-9519R    BPGM紅細(xì)胞2,3 - 二磷酸甘油酸合成酶抗體
xy-2229R    Brucella布氏桿菌菌體蛋白抗體
xy-3373R    phospho-B-Raf (Ser444)磷酸化B-Raf抗體
xy-3374R    phospho-B-Raf (Ser602)磷酸化B-Raf抗體
xy-3542R    PNK1多聚合苷酸激酶3磷酸化酶抗體
xy-0803R    BRCA1乳腺癌易感基因1抗體
xy-1284R    BakBcl-2同源拮抗劑抗體
xy-1063R    beta 3 Adrenergic Receptorβ3腎上腺素能受體抗體
xy-4865R    BNP腦鈉素/利鈉肽抗體
xy-8726R    BZW2BZW2蛋白抗體
xy-8675R    BDKRB1緩激肽B1受體抗體
xy-4775R    BK channel鈣激活鉀通道蛋白α1抗體
xy-11041R    Bestrophin 2卵黃狀黃斑病蛋白2抗體