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甲狀腺激素受體α1+α2抗體

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品       牌Abcam

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所  在  地上海

更新時間:2015-06-10 10:00:22瀏覽次數:270次

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甲狀腺激素受體α1+α2抗體
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.

甲狀腺激素受體α1+α2抗體

英文名稱 THRA1+2
中文名稱 甲狀腺激素受體α1+α2抗體
別    名 Thyroid Hormone Receptor alpha 1+2; THRA1+THRA2; AR7; Avian erythroblastic leukemia viral (v erb a) oncogene homolog; c ERBA 1; c ERBA ALPHA 2; C erbA alpha; c-erbA-1; C-erbA-alpha; cerbA protein; cerbAalpha; EAR 7; EAR 7.1; EAR 7.2; EAR-7; EAR7; ERB T 1; ERBA 1; ERBA ALPHA; ERBA; ERBA related 7; ERBA1; Erythroblastic leukemia viral (v erb a) oncogene homolog avian; NR1A 1; Nr1a1; Nuclear receptor subfamily 1 group A member 1; Oncogene ERBA; THA_HUMAN; THRA; Thra1; Thra2; Thyroid hormone receptor alpha 1 (avian erythroblastic leukemia viral (verba) oncogene homolog 1 formerly ERBA1); Thyroid hormone receptor alpha 1; Thyroid hormone receptor alpha 2; Thyroid hormone receptor alpha; TR alpha 1; TR alpha 2; Tra1; Triiodothyronine receptor; V-erbA-related protein 7.

說 明 書 0.2ml  
研究領域 腫瘤  細胞生物  染色質和核信號  神經生物學  信號轉導  轉錄調節(jié)因子  內分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Zebrafish, Sheep, Cat, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
細胞定位 細胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human THRA1 and THRA2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

Function:
Nuclear hormone receptor. High affinity receptor for triiodothyronine.

Subunit:
Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Probably interacts with SFPQ. Interacts with C1D (By similarity). Interacts with AKAP13.

Subcellular Location:
Nucleus.
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