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酮基移換酶樣蛋白1抗體

英文名稱 TKTL1
中文名稱 酮基移換酶樣蛋白1抗體
別    名 TK 2; TK2; TKR; TKT 2; TKT2; TKTL1; TKTL1_HUMAN; Transketolase 2; Transketolase like 1; Transketolase like protein 1; Transketolase related protein; Transketolase-like protein 1; Transketolase-related protein; Transketolase2.
   
說 明 書 0.1ml  0.2ml  
研究領域 腫瘤  信號轉導  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65 kDa
細胞定位 細胞核 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TKTL1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene.

Function:
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate 

Subunit:
Homodimer 

Subcellular Location:
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic and to a lesser extent also nuclear.

Tissue Specificity:
Expressed in fetal and adult heart, brain, lung, liver, and kidney, and in adult placenta, skeletal muscle and pancreas. Up-regulated in various epithelial tumors. 

Similarity:
Belongs to the transketolase family. xy-5243R    phospho-Cdc25B (Ser323)磷酸化細胞分裂周期蛋白25B抗體
xy-5244R    phospho-Cdc25B (Ser186)磷酸化細胞分裂周期蛋白25B抗體
xy-5240R    phospho-Caspase 6 (Ser257)磷酸化半胱胺酸蛋白酶蛋白6抗體
xy-15320R    C9orf1729號染色體開放閱讀框172抗體
xy-5227R    phospho-CDKN1B (Ser10)磷酸化P27抗體/周期素依賴激酶抑制劑
xy-9383R    CNOT2細胞表面趨化因子受體4相關蛋白2抗體
xy-5047R    CPT2肉毒堿棕櫚酰基轉移酶2抗體
xy-5048R    CROT肉堿氧位甲基轉移酶抗體
xy-5044R    COL4A3BPIV型膠原α3結合蛋白抗體
xy-5045R    CPT1B肉毒堿棕櫚?；D移酶1B抗體
xy-5049R    CYP27A1膽固醇27α羥化酶抗體
xy-5050R    CYP39A1膽固醇24α7羥化酶抗體
xy-5054R    CYP4A1細胞色素P450 4A1抗體
xy-5055R    CYP4A22細胞色素P4504A22抗體（脂肪酸Ω羥化酶）
xy-5982R    CDKN2D細胞周期蛋白依賴性激酶抑制劑2D抗體
xy-5046R    CYP46膽固醇24S－羥化酶
xy-4528R    CSFV Polyprotein豬瘟病毒抗體
xy-2376R    Cytochrome c oxidase subunit 2細胞色素c氧化酶亞型2抗體
xy-3822R    Cyclin G2周期素G2抗體
xy-2373R    Ceruloplasmin銅藍蛋白抗體
xy-4608R    CUEDC2CUE結構域蛋白2抗體
xy-3890R    NDUFS1(75kD)線粒體復合物NDUFS1蛋白抗體
xy-4019R    Thromboxane synthase血栓素合成酶抗體
xy-3878R    CQ028多癌基因下調蛋白抗體
xy-3931R    COX 5B細胞色素C氧化酶蛋白5B抗體
xy-3934R    COX3細胞色素C氧化酶亞基3抗體
xy-3935R    COX6B細胞色素C氧化酶亞基6B抗體
xy-4017R    phospho-C-Myc(Thr358)磷酸化致癌基因C-Myc抗體
xy-4018R    phospho-C-Myc (Thr373)磷酸化致癌基因C-Myc抗體
xy-3898R    CYP11B1細胞色素P450 11B1抗體
xy-3892R    cGMP環(huán)磷酸鳥苷抗體
xy-3901R    Cubilin內皮因子維生素B12受體抗體