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膜型絲氨酸蛋白酶2抗體

英文名稱 TMPRSS4
中文名稱 膜型絲氨酸蛋白酶2抗體
別    名 MT SP2; Membrane type serine protease 2; TMPRSS 4; TMPRSS3; Transmembrane protease, serine 4; Transmembrane serine protease 3; UNQ776/PRO1570; TMPS4_HUMAN.
 
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  腫瘤細(xì)胞生物標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Horse, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TMPRSS4 (84-130aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
TMPRSS4 is a member of the peptidase S1 family and contains 1 LDL receptor class A domain, 1 peptidase S1 domain and 1 SRCR domain. It is a probable membrane protease capable of activating ENaC and may process sodium channels in endothelial cells. TMPRSS4 is overexpressed in thyroid neoplasms, and splice variants in TMPRSS4 are thought to be linked with different cancers. Three named isoforms are produced by alternative splicing.

Function:
Probable protease. Seems to be capable of activating ENaC.

Subcellular Location:
Membrane; Single-pass type II membrane protein (Potential).

Tissue Specificity:
High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.xy-5976R    c-Maf原癌基因cMAF抗體
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xy-15168R    C3orf223號(hào)染色體開放閱讀框22抗體
xy-9682R    C19orf4619號(hào)染色體開放閱讀框46抗體
xy-5977R    c-Maf原癌基因cMAF抗體
xy-3930R    CACNA1A電壓依賴性鈣通道Cav2.1抗體
xy-3932R    CACH3L型鈣通道蛋白a1亞型3抗體
xy-3933R    CACH6L型鈣通道蛋白a1亞型6抗體
xy-2352R    Cytochrome P450 2B6細(xì)胞色素P450 2B6抗體
xy-5265R    phospho-CTNNBIP1 (Ser36)磷酸化β鏈接素相互作用蛋白1抗體
xy-15112R    C20orf6220號(hào)染色體開放閱讀框62抗體
xy-4262R    cIAP1凋亡抑制因子1抗體
xy-15108R    C20orf2720號(hào)染色體開放閱讀框27抗體
xy-6187R    C1 Inactivator酯酶抑制蛋白C1IN抗體
xy-6277R    CYP2W1細(xì)胞色素P450 2W1抗體
xy-6278R    Choline dehydrogenase膽堿脫氫酶抗體
xy-5764R    CIAPIN1細(xì)胞因子誘導(dǎo)凋亡抑制因子1
xy-6609R    Cyclophilin B親環(huán)蛋白PPIB抗體
xy-6226R    CT13腫瘤/睪丸抗原13抗體
xy-4267R    CDKN2AIP鈣反應(yīng)因子抗體
xy-5746R    CDC2L1細(xì)胞分裂周期蛋白2亞型1抗體
xy-15116R    C20orf74 20號(hào)染色體開放閱讀框74抗體
xy-6620R    CRHR2促腎上腺皮質(zhì)釋放激素受體2抗體
xy-9694R    C20orf13220號(hào)染色體開放閱讀框132抗體
xy-4595R    Collagen IVIV型膠原蛋白/4型膠原蛋白/膠原蛋白4抗體
xy-4247R    CHRNB2煙堿型乙酰膽堿受體B2抗體
xy-15114R    C20orf70 20號(hào)染色體開放閱讀框70抗體
xy-5911R    Cyclophilin B親環(huán)蛋白（親環(huán)素）PPIB抗體
xy-15287R    C8ORF348號(hào)染色體開放閱讀框34抗體