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轉(zhuǎn)導(dǎo)素β1X連鎖蛋白抗體

英文名稱 TBL1X/SMAP55
中文名稱 轉(zhuǎn)導(dǎo)素β1X連鎖蛋白抗體
別    名 TBL1; EBI; F box like/WD repeat protein TBL1X; SMAP 55; SMAP55; TBL 1; TBL1X; Transducin (beta) like 1; Transducin (beta) like 1 X linked; Transducin beta like 1 X linked; Transducin beta like 1X; Transducin beta like 1X protein; TBL1X_HUMAN; F-box-like/WD repeat-containing protein TBL1X; Full=Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linked. .

說(shuō) 明 書(shū) 0.2ml  
研究領(lǐng)域 腫瘤  免疫學(xué)  染色質(zhì)和核信號(hào)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TBL1X
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq].

Function:
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.xy-1060R    Cytokeratin 5細(xì)胞角蛋白5抗體
xy-1106R    CK8細(xì)胞角蛋白8抗體
xy-0548R    MERTKc-mer原癌基因酪氨酸激酶抗體
xy-0709R    Collagen IIⅡ型膠原α1蛋白/軟骨鈣素抗體
xy-0549R    Collagen IIIⅢ型膠原蛋白/膠原蛋白3/3型膠原蛋白抗體
xy-0806R    Collagen IVIV型膠原蛋白/4型膠原蛋白/膠原蛋白4抗體
xy-0582R    Cyclooxygenase 1前列腺素氧化環(huán)化酶1抗體
xy-0578R    Collagen IⅠ型膠原抗體
xy-0552R    Collagen VⅤ型膠原抗體
xy-0554R    Collagen XⅩ型膠原抗體
xy-1686R    Cyclin F周期素F抗體
xy-9127R    Cullin 7泛素連接酶CUL7蛋白抗體
xy-9125R    COPS2甲狀腺受體相互作用蛋白15抗體
xy-9120R    COPS6信號(hào)轉(zhuǎn)導(dǎo)蛋白亞基6抗體
xy-9123R    COPS4信號(hào)轉(zhuǎn)導(dǎo)蛋白亞基4抗體
xy-0799R    cardiac Troponin I心肌肌鈣蛋白抗體
xy-1306R    CAP1CAP1抗體
xy-1023R    CSF3粒細(xì)胞-巨噬細(xì)胞集落刺激因子3抗體
xy-1305R    CCR7細(xì)胞表面趨化因子受體7抗體
xy-0618R    COX10細(xì)胞色素c氧化酶10抗體
xy-2546R    CRTAMCRTAM抗體
xy-2468R    MCP4單核細(xì)胞趨化蛋白4抗體
xy-2642R    KIR2DL3NK細(xì)胞抑制性受體2DL3抗體
xy-3798R    CRX1CRX抗體
xy-0648R    CD8CD8抗體
xy-3089R    phospho-CBL2 (Tyr731)磷酸化原癌蛋白CBL2抗體
xy-3090R    phospho-CBL2 (Tyr774)磷酸化原癌蛋白CBL2抗體
xy-3091R    Phospho-cdc2 (Thr14)磷酸化周期素依賴激酶2抗體
xy-3092R    Phospho-cdc2 (Tyr15)磷酸化周期素依賴激酶2抗體
xy-2758R    Cdc25A細(xì)胞分裂周期蛋白25抗體
xy-3093R    Phospho-cdc25A (Thr506)磷酸化細(xì)胞分裂周期蛋白25抗體
xy-3094R    Phospho-cdc25A (Ser76)磷酸化細(xì)胞分裂周期蛋白25抗體
xy-3095R    Phospho-cdc25A (Ser178)磷酸化細(xì)胞分裂周期蛋白25抗體
xy-6463R    caspase-8 subunit p18半胱氨酸蛋白酶8抗體
xy-8502R    caspase-9 p10半胱胺酸蛋白酶蛋白9-p10抗體
xy-2663R    CLEC5AC型凝集素結(jié)構(gòu)域家族5成員A抗體
xy-1341R    CDK1周期素依賴激酶1抗體
xy-0793R    RSL1D1細(xì)胞衰老抑制基因抗體