線粒體硫氧還蛋白2抗體 返回列表頁

線粒體硫氧還蛋白2抗體

英文名稱 Thioredoxin 2
中文名稱 線粒體硫氧還蛋白2抗體
別    名 mitochondrial thioredoxin; MT-TRX; MTRX; thioredoxin 2 precursor; Thioredoxin mitochondrial; Thioredoxin2; TRX 2; TRX2; TXN 2; TXN2.
  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  免疫學(xué)  腫瘤細(xì)胞生物標(biāo)志物  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
細(xì)胞定位 細(xì)胞漿 線粒體
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Thioredoxin 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

Function:
Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity. xy-12953R    Desmoplakin I+II橋粒斑蛋白1+2抗體
xy-10152R    Desmoglein 2橋粒芯糖蛋白2抗體
xy-12245R    DAZL生殖細(xì)胞發(fā)育相關(guān)蛋白DAZL抗體
xy-7416R    DNA polymerase deltaDNA聚合酶γ抗體
xy-7352R    DR5死亡受體5抗體
xy-13744R    Desmoglein 4橋粒芯糖蛋白4抗體
xy-10522R    DAP12自然殺傷激活受體相關(guān)蛋白DAP12抗體
xy-12630R    DAP12自然殺傷激活受體相關(guān)蛋白DAP12抗體
xy-13609R    DAZ4無精癥缺失基因4抗體
xy-13595R    Dppa4多能發(fā)育相關(guān)基因4抗體
xy-13594R    DZIP1鋅指蛋白DZIP1抗體
xy-7345R    DLL1Notch信號通路Delta樣配體1抗體
xy-6467R    Dlx1同源轉(zhuǎn)錄因子DLX1抗體
xy-4290R    CDC37Hsp90輔助伴侶分子CDC37抗體
xy-6718R    Dystrophin肌營養(yǎng)不良蛋白抗體
xy-3577R    Dematin金屬離子轉(zhuǎn)運體1抗體
xy-2162R    DKK1抑癌蛋白DKK1抗體
xy-11549R    Dispatched膜轉(zhuǎn)運蛋白DISPA抗體
xy-13003R    DIRAS2DIRAS2蛋白抗體
xy-0993R    DDX58DDX58抗體
xy-3597R    DDX4DDX4抗體
xy-1672R    Duck plague virus鴨瘟病毒DPV抗體
xy-3514R    D-DIMER交聯(lián)纖維蛋白二聚體抗體
xy-5835R    Drebrin腦發(fā)育調(diào)節(jié)蛋白抗體
xy-7648R    DFFBDNA斷裂因子抗體（蛋白酶激活脫氧核糖核酸酶）
xy-7653R    DNase gamma脫氧核糖核酸酶γ抗體
xy-7659R    DATF1死亡相關(guān)轉(zhuǎn)錄因子1抗體
xy-7651R    DNase I脫氧核糖核酸酶1抗體
xy-7652R    DNase II脫氧核糖核酸酶2抗體
xy-6800R    DAD1細(xì)胞死亡防衛(wèi)蛋白1抗體
xy-7592R    DARCDuffy血型趨化因子受體抗體