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轉化酸性卷曲含蛋白質2

英文名稱 TACC2
中文名稱 轉化酸性卷曲含蛋白質2
別    名 TACC2_HUMAN; Anti zuai 1; AZU 1; AZU1; ECTACC; TACC 2; Transforming acidic coiled coil containing protein 2.

說 明 書 0.1ml  0.2ml  
研究領域 腫瘤  細胞生物  免疫學  細胞周期蛋白  細胞分化  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Cow, Rabbit, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 309kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TACC2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產品介紹 background:
TACC2 is a conserved family of centrosome and microtubule interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is thought to affect the progression of breast tumors. Expression of this gene is also induced by erythropoietin.

Function:
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker. 

Subunit:
Interacts with CCDC100/CEP120 (By similarity). Interacts with microtubules. Interacts with YEATS4, GCN5L2 and PCAF. 

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, centrosome. xy-1714R    DAT多巴胺轉運蛋白DAT抗體
xy-1694R    DcR2誘捕受體2抗體
xy-1696R    DR5腫瘤細胞調亡素/死亡受體5抗體
xy-1695R    DCN/Decorin 核心蛋白聚糖抗體
xy-7609R    DUSP2雙特異性磷酸酶2抗體
xy-9312R    C21orf10621號染色體開放閱讀框106抗體
xy-6974R    Dlx5同源轉錄因子DLX5抗體
xy-9467R    DVL3DVL3蛋白抗體
xy-1359R    DNA PKcsDNA依賴蛋白激酶催化亞基抗體
xy-1361R    DDIT3GADD153抗體
xy-8555R    Desmuslin中間絲蛋白β-synemin抗體
xy-9669R    DENND4CMAP激酶激活死亡域蛋白4C抗體
xy-9926R    Desmocollin 4橋粒糖蛋白4抗體
xy-11343R    Dynamin 3酶動力蛋白3抗體
xy-7000R    Delta Cateninδ連環(huán)蛋白/δ連環(huán)素/δ鏈接素（δ-catenin）抗體
xy-11066R    DOK6胞漿接頭蛋白Dok6抗體
xy-8587R    DOK5胞漿接頭蛋白Dok5抗體
xy-9394R    DCAF12睪丸癌中心體相關蛋白抗體
xy-9395R    DCAF13DCAF13蛋白抗體
xy-6999R    DCHS1原鈣粘蛋白16抗體
xy-6998R    ERR-alpha雌激素受體相關蛋白α抗體
xy-8291R    DPY19L2DPY19L2蛋白抗體
xy-8288R    DPYD二氫嘧啶脫氫酶抗體
xy-8289R    DPY19L1短粗矮胖19蛋白樣1抗體
xy-8292R    DPY19L4DPY19L4蛋白抗體
xy-8294R    DPP9二肽基肽酶9抗體
xy-8295R    DPP8二肽基肽酶8抗體
xy-12037R    DRD4多巴胺受體D4抗體
xy-8293R    DQX1DQX1蛋白抗體
xy-7117R    DDX5三磷酸腺苷依賴解旋酶ddx5抗體
xy-8005R    phospho-DDX5 (Tyr593)磷酸化三磷酸腺苷依賴解旋酶ddx5抗體
xy-11862R    DYX2/KIAA0319閱讀障礙相關蛋白DLX2抗體
xy-10046R    Dystrobrevin alpha肌營養(yǎng)蛋白α抗體
xy-10064R    CD299CD299抗體
xy-11546R    DUSP6雙特異性蛋白磷酸酶6/絲裂原活化蛋白激酶磷酸酶3抗體