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腫瘤壞死因子配體超家族成員9抗體

參   考   價: 80

訂  貨  量: ≥1 

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產(chǎn)品型號

品       牌Abcam

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所  在  地上海

更新時間:2015-06-10 10:35:30瀏覽次數(shù):263次

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腫瘤壞死因子配體超家族成員9抗體
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.

腫瘤壞死因子配體超家族成員9抗體

英文名稱 TNFSF9
中文名稱 腫瘤壞死因子配體超家族成員9抗體
別    名 4 1BB L; 4 1BB ligand; 4 1BBL; Cd137l; Cd157l; homolog of mouse 4 1BB L; homolog of mouse 4 1BBL; ILA ligand (TNF related); Ly63l; receptor 4 1BB ligand; Tumor necrosis factor (ligand) superfamily member 9.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細胞生物  免疫學  神經(jīng)生物學  細胞表面分子  t-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25-27kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNFSF9
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This cytokine belongs to the tumour necrosis factor (TNF) ligand family. It is a ligand for TNFRSF9, which is a costimulatory molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process, and in the generation of cytotoxic T cells. This cytokine is also shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is found to be expressed in various carcinoma cell lines, and is thought to be involved in T cell-tumour cell interaction.

Function:
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

Subunit:
Homotrimer.

Subcellular Location:
Membrane; Single-pass type II membrane protein.
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xy-5484R    phospho-ERK5 (Ser496)磷酸化細胞外信號調(diào)節(jié)激酶5抗體
xy-5486R    phospho-ERK5 ( Ser731+Thr733)磷酸化細胞外信號調(diào)節(jié)激酶5抗體
xy-4131R    ERK4細胞外信號調(diào)節(jié)激酶4抗體
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