Toll樣受體9抗體 返回列表頁

Toll樣受體9抗體

英文名稱 TLR9
中文名稱 Toll樣受體9抗體
別    名 Toll-like receptor 9; CD 289; CD289; TLR 9; Toll like receptor 9; Toll like receptor 9 isoform A precursor; Toll like receptor 9 isoform B; TLR9_HUMAN.
  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 113kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TLR9
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]

Function:
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection.

Subunit:
Interacts with MYD88 via their respective TIR domains. Interacts with CNPY3. Interacts (via transmembrane domain) with UNC93B1. Interacts with BTK.xy-13210R    FOXRED2FOXRED2蛋白抗體
xy-13211R    FPGT巖藻糖1磷酸鳥苷酰轉(zhuǎn)移酶抗體
xy-13213R    FREM1細(xì)胞外基質(zhì)蛋白FREM1抗體
xy-12434R    FRAT1原癌基因FRAT1抗體
xy-12193R    FOXD1叉頭蛋白D1抗體
xy-10336R    Factor XI heavy chain凝血因子11重鏈抗體
xy-10337R    Factor XII light chain凝血因子12輕鏈抗體
xy-0879R    FLAG Tag (CT)FLAG Tag標(biāo)簽抗體（C端）
xy-10339R    Factor I heavy chain補(bǔ)體因子I重鏈抗體
xy-10417R    Factor VIIIa light chain凝血因子8/第八凝血因子/第八因子相關(guān)抗原輕鏈抗體
xy-3144R    phospho-FOXO4 (Ser197)磷酸化叉頭蛋白4抗體
xy-3145R    phospho-FOXO4 (Ser262)磷酸化叉頭蛋白4抗體
xy-2572R    FPR1甲酸基肽受體1抗體
xy-5539R    phospho-FAK(Ser722)磷酸化粘著斑激酶抗體
xy-10182R    FUT5FUT5抗體
xy-1548R    FOXO3A叉頭蛋白O3A抗體
xy-6050R    FSTL1卵泡相關(guān)蛋白1
xy-6049R    FGFR5成纖維細(xì)胞生長(zhǎng)因子受體5抗體
xy-1642R    phospho-FAK(Ser732)磷酸化粘著斑激酶抗體
xy-3164R    Phospho-FAK (Tyr407)磷酸化粘著斑激酶抗體
xy-4522R    FMDV Polyprotein (3A protein) 口蹄疫病毒A型抗體
xy-9088R    FBXO28FBXO28蛋白抗體
xy-9083R    FBXW5FBXW5蛋白抗體
xy-9084R    FBXW12FBXW12蛋白抗體
xy-9085R    FBXO42FBXO42蛋白抗體
xy-0216R    Fas LigandFasL抗體
xy-1157R    Fibrillin 1原纖維蛋白1抗體
xy-0711R    FAM3B/PANDER胰腺衍生因子抗體
xy-0229R    FGF1酸性成纖維細(xì)胞生長(zhǎng)因子抗體
xy-0332R    factor VIII凝血因子8/第八凝血因子/第八因子相關(guān)抗原抗體
xy-0434R    factor VIII凝血因子8/第八凝血因子/第八因子相關(guān)抗原抗體
xy-0511R    FADDFas死亡結(jié)構(gòu)域相關(guān)蛋白
xy-0773R    FAM3A胰腺衍生因子抗體