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腫瘤抑素抗體

英文名稱(chēng) Tumstatin
中文名稱(chēng) 腫瘤抑素抗體
別    名 Collagen alpha-3(IV) chain; Alpha 3 type IV collagen; Alpha3 type IV collagen; COL4A 3; COL4A3; Collagen IV alpha 3 polypeptide; Collagen type IV alpha 3 (Goodpasture antigen); Collagen type IV alpha 3; Goodpasture antigen; OTTHUMP00000195044; Tumstatin; Col4a3; CO4A3_HUMAN.
  
說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  膠原蛋白  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:200-1000 ELISA=1:500-1000 IHC-P=1:100-600 IHC-F=1:100-600 IF=1:100-600 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27/159kDa
細(xì)胞定位 細(xì)胞膜 細(xì)胞外基質(zhì) 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Tumstatin
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In the Goodpasture syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein. A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jun 2010]xy-12020R    GPR101G蛋白偶聯(lián)受體101抗體
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xy-10122R    phospho-gp130 (Ser782)磷酸化gp130抗體
xy-13442R    Glutathione Transferase zeta 1谷胱甘肽S轉(zhuǎn)移酶ζ1抗體
xy-13443R    GLYAT甘胺酸-N-?；D(zhuǎn)移酶抗體
xy-13444R    GLYATL1甘胺酸-N-?；D(zhuǎn)移酶樣1抗體
xy-13445R    G3PP 轉(zhuǎn)運(yùn)蛋白G3PP抗體
xy-13446R    Phospho-Glycogen synthase 1(Ser645)磷酸化葡萄糖合成酶1抗體
xy-13447R    Glycogenin 1糖原蛋白1
xy-13640R    GRAP生長(zhǎng)因子受體結(jié)合蛋白2相關(guān)接頭蛋白抗體
xy-13641R    GRB 14生長(zhǎng)因子受體結(jié)合蛋白14抗體
xy-13448R    GLYCTKHBeAg結(jié)合蛋白4/甘油激酶抗體
xy-13449R    GLYATL2甘胺酸-N-?；D(zhuǎn)移酶樣2抗體
xy-13450R    Glypican 2磷脂?；嫉鞍拙厶?抗體
xy-13451R    GLYR1氧化還原酶GlyR1/核蛋白60抗體
xy-13452R    GM2A神經(jīng)鞘脂激活蛋白3抗體
xy-13453R    GMDS甘露糖脫水酶GMDS抗體
xy-13454R    GMEB1糖皮質(zhì)激素調(diào)節(jié)元件結(jié)合蛋白1抗體
xy-13456R    GMEB2糖皮質(zhì)激素調(diào)節(jié)元件結(jié)合蛋白2抗體
xy-13457R    GMFG膠漿成熟因子γ/GMF-γ抗體
xy-13459R    GMP Synthase谷氨酰胺轉(zhuǎn)移酶GMPS抗體
xy-13461R    GMPPBGDP甘露糖焦磷酸化酶B抗體
xy-8874R    GPBAR1G蛋白偶聯(lián)膽汁酸受體1
xy-13473R    GNPDA1葡萄糖6-磷酸脫氨酶1抗體
xy-13474R    GNPDA2葡萄糖6-磷酸脫氨酶2抗體
xy-13475R    GNPNAT1葡萄糖6-N-乙酰基轉(zhuǎn)移酶1抗體
xy-10341R    GLS1谷氨酰胺酶1抗體
xy-15385R    GPR161G蛋白偶聯(lián)受體GPR161蛋白抗體
xy-15389R    GPR180G蛋白偶聯(lián)受體GPR180蛋白抗體