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當(dāng)前位置:上海信裕生物科技有限公司>>抗體>>一抗>> 腫瘤壞死因子配體超家族成員4抗體
產(chǎn)品型號(hào)
品 牌Abcam
廠商性質(zhì)生產(chǎn)商
所 在 地上海
更新時(shí)間:2015-06-10 11:13:07瀏覽次數(shù):277次
聯(lián)系我時(shí),請(qǐng)告知來自 化工儀器網(wǎng)腫瘤壞死因子配體超家族成員4抗體
英文名稱 TNFSF4
中文名稱 腫瘤壞死因子配體超家族成員4抗體
別 名 CD 134L; CD 252; CD134; CD134 ligand; CD134L; CD252; CD252 antigen; glycoprotein 34 kd; Glycoprotein Gp34; GP34; OX-40L; OX40 antigen ligand; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; TNFL4_RAT; Tnfsf4; Tumor necrosis factor (ligand) superfamily member 4; Tumor necrosis factor ligand superfamily member 4; TXGP1.
說 明 書 0.1ml 0.2ml
研究領(lǐng)域 細(xì)胞生物 免疫學(xué) 細(xì)胞表面分子 淋巴細(xì)胞 t-淋巴細(xì)胞 細(xì)胞因子
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,
產(chǎn)品應(yīng)用 IHC-P=1:100-500 IHC-F=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
細(xì)胞定位 細(xì)胞膜
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from rat TNFSF4
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq]
Function:
Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
Subunit:
Homotrimer (Probable).
Subcellular Location:
Membrane; Single-pass type II membrane protein.
Tissue Specificity:
Detected in T-cell lines, but not in a macrophage cell line.
Similarity:
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