Toll樣受體11抗體 返回列表頁

Toll樣受體11抗體

英文名稱 TLR11
中文名稱 Toll樣受體11抗體
別    名 Toll like receptor 11; Gm287; MGC129352; MGC129353; RGD1564460; TLR11_MOUSE.
   
說 明 書 0.2ml  
研究領(lǐng)域 免疫學(xué)  細(xì)胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 99kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse TLR11
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Toll like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR11 is one of three mouse TLRs that lack a human ortholog. It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system.

Function:
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Subunit:
Binds MYD88 via their respective TIR domains. Interacts with HSP90B1; this interaction is required for proper folding in the endoplasmic reticulum.xy-13394R    Glutaredoxin 2谷氧還蛋白2抗體
xy-13395R    Glutaredoxin 5谷氧還蛋白5抗體
xy-13396R    GPX2谷胱甘肽過氧化酶2抗體
xy-13397R    GPX7谷胱甘肽過氧化酶7抗體
xy-13398R    GSTA1谷胱甘肽S轉(zhuǎn)移酶α1抗體
xy-13399R    GSTK1谷胱甘肽S轉(zhuǎn)移酶κ抗體
xy-3983R    Galactose kinase半乳糖激酶1抗體
xy-3991R    GYG2糖原蛋白2抗體
xy-3984R    GALT磷酸半乳糖尿苷酸轉(zhuǎn)移酶1抗體
xy-3990R    GYG1糖原蛋白1抗體
xy-3989R    Glycogen synthase 2葡萄糖合成酶2抗體
xy-3985R    GOT2谷草轉(zhuǎn)氨酶2抗體
xy-3987R    Glucose 6 Phosphate Dehydrogenase葡萄糖-6磷酸脫氫酶抗體
xy-3988R    GLUT5葡萄糖轉(zhuǎn)運(yùn)蛋白5抗體
xy-2359R    Glycogen葡萄糖合成酶1抗體
xy-13502R    GPATCH8G蛋白修補(bǔ)結(jié)構(gòu)域蛋白8抗體
xy-13368R    GK3甘油激酶3抗體
xy-13489R    GOLPH3L高爾基體磷蛋白3樣蛋白抗體
xy-8446R    phospho-GluR1 (Ser849)磷酸化谷氨酸受體1抗體
xy-13498R    GPATCH1/ECGPG蛋白修補(bǔ)結(jié)構(gòu)域蛋白1抗體
xy-5374R    phospho-GIT1(Tyr510) 磷酸化G蛋白偶聯(lián)受體激酶相互作用蛋白1抗體
xy-5373R    phospho-GIT1(Tyr554) 磷酸化G蛋白偶聯(lián)受體激酶相互作用蛋白1
xy-2356R    GKRP葡萄糖激酶調(diào)節(jié)蛋白抗體
xy-3893R    GTPBP10GTP結(jié)合蛋白10抗體
xy-5376R    phospho-G3BP1(Ser232)磷酸化Ras GTP酶活化蛋白結(jié)合蛋白1抗體
xy-4111R    G3BP1Ras GTP酶活化蛋白結(jié)合蛋白1抗體
xy-4112R    GABA A Receptor gamma 2γ氨基丁酸γ2受體/GABAA Rγ2抗體
xy-5367R    phospho-GSK-3 Beta(Ser21+Ser29)磷酸化糖原合酶激酶3β抗體
xy-5372R    phospho-GIT1(Ser375)磷酸化G蛋白偶聯(lián)受體激酶相互作用蛋白1抗體
xy-5369R    phospho-GATA1(ser142)磷酸化珠蛋白轉(zhuǎn)錄因子1抗體
xy-5370R    phospho-GATA1(ser310)磷酸化珠蛋白轉(zhuǎn)錄因子1抗體
xy-4110R    GIT1G蛋白偶聯(lián)受體激酶相互作用蛋白1抗體
xy-5375R    phospho-GATA6(Tyr271)磷酸化GATA結(jié)合蛋白6抗體
xy-5377R    phospho-GABRG2(Ser327)磷酸化γ氨基丁酸γ2受體/GABAA Rγ2抗體
xy-3945R    Glucagon Receptor胰高血糖素受體抗體