神經(jīng)干細(xì)胞抑制相關(guān)蛋白TRIM32抗體 返回列表頁

神經(jīng)干細(xì)胞抑制相關(guān)蛋白TRIM32抗體

英文名稱 TRIM32
中文名稱 神經(jīng)干細(xì)胞抑制相關(guān)蛋白TRIM32抗體
別    名 72 kda Tat interacting Protein; BBS11; HT2A; LGMD2H; Limb girdle muscular dystrophy 2H (autosomal recessive); Limb girdle muscular dystrophy 2H; Muscular dystrophy Hutterite type; TAT interactive protein 72KD; TATIP; Tripartite Motif Containing Protein 32; Zinc Finger Protein HT2A; TRI32_MOUSE.
  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  干細(xì)胞  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 72kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse TRIM32
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family. TRIM32, like all TRIM proteins, contains a domain structure composed of a B-box, a RING-finger and a coiled-coil motif. Additionally, TRIM32 has six C-terminal NHL domains; it is expressed mainly in the skeletal muscle. The TRIM32 gene encodes an E3 ubiquitin ligase, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, UbcH5c and UbcH6. Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM). TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), an autosomal recessive disorder characterized by pigmentary retinopathy, polydactyly, hypogenitalism, renal abnormalities, learning disabilities and obesity.

Function:
Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) (By similarity). Ubiquitinates PIAS4/PIASY and promotes its degradation in keratinocytes treated with UVB and TNF-alpha.xy-2001R    H1N1 Hemagglutinin 1甲型流感病毒血凝素抗體
xy-3213R    Phospho-HER2(Tyr1112)磷酸化HER2受體抗體
xy-2809R    HDAC4組蛋白去乙?；?抗體
xy-3212R    Phospho-HER2 (Tyr1221 + Tyr1222)磷酸化HER2受體抗體
xy-3127R    phospho-HDAC8 (Ser39)磷酸化組蛋白去乙?；?抗體
xy-1198R    HLA-DRHLA-DR抗體
xy-0752R    HLA G人類白細(xì)胞抗原G抗體
xy-0556R    HMGA2高遷移率族蛋白A2抗體
xy-0664R    HMGB1高遷移率族蛋白B1抗體
xy-1238R    HO-2血紅素氧合酶2抗體
xy-0394R    HOXc8HOXc8抗體
xy-1071R    HRAS原癌基因H-ras抗體
xy-0191R    HSP60熱休克蛋白-60抗體
xy-0126R    HSP70熱休克蛋白-70抗體
xy-0696R    HSP90 alpha熱休克蛋白90α抗體
xy-0135R    HSP90 beta熱休克蛋白90β/HSP90 β 抗體
xy-0896R    HCMV UL23人巨細(xì)胞病毒UL23抗體
xy-9702R    HECAHECA蛋白抗體
xy-9091R    hnRNP A2B1異質(zhì)核糖核蛋白hnRNPA2抗體
xy-9092R    hnRNP U異質(zhì)核糖核蛋白U抗體
xy-1719R    HPV16 E6 + HPV18 E6人類乳頭狀瘤病毒16/18 E6抗體
xy-0843R    HA tagHA tag標(biāo)簽抗體
xy-0455R    HSL/LIPE荷爾蒙敏感脂肪酶抗體
xy-0847R    HBA1血紅蛋白α1/α-Globin抗體
xy-6353R    HIPK2Fas相互作用蛋白激酶2抗體
xy-6777R    HIPK3Fas相互作用蛋白激酶3抗體
xy-0860R    HHV8 ORF50人類皰疹病毒8抗體
xy-3180R    Phospho-HSP27 (Ser82)磷酸化熱休克蛋白27抗體