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腫瘤易感基因101蛋白抗體

英文名稱 Tsg101
中文名稱 腫瘤易感基因101蛋白抗體
別    名 ESCRT I complex subunit TSG101; ESCRT-I complex subunit TSG101; Tsg101; TSG 10; TSG 101; TSG10; Tumor susceptibility gene 10; Tumor susceptibility gene 101; Tumor susceptibility gene 101 protein; Tumor susceptibility protein; Tumor susceptibility protein isoform 3; VPS 23; VPS23; TS101_HUMAN.

說 明 書 0.1ml  0.2ml  
研究領域 腫瘤  細胞生物  免疫學  染色質(zhì)和核信號  微生物學  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
細胞定位 細胞核 細胞漿 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Tsg101 N-terminus
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:

The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. TSG101 also interacts with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses like HIV-1 p6, human spumavirus Gag, HTLV-1 Gag, as well as of Ebolavirus VP40.xy-4715R    Histone H3 (Tri Methyl K4)*基化組蛋白H3抗體
xy-5068R    HMGCR三羥基*基輔酶A還原酶抗體
xy-5072R    Heparan Sulfate Proteoglycan 2硫酸乙酰肝素蛋白多糖2
xy-15421R    HCA25a肝癌相關抗原h(huán)ca25a
xy-3994R    Hexokinase 3己糖激酶3抗體
xy-2327R    HBV pre S1 protein人乙肝病毒pre S1/S2蛋白抗體
xy-2328R    HBV pre S1 protein人乙肝病毒pre S1蛋白抗體
xy-3992R    Hexokinase 1己糖激酶1抗體
xy-3993R    Hexokinase 2己糖激酶2抗體
xy-10100R    HSP90 alpha熱休克蛋白90α抗體
xy-6894R    HFREP1肝細胞源性纖維蛋白原相關蛋白1抗體
xy-12303R    Hemogen紅細胞分化相關基因蛋白抗體
xy-12244R    HOXA13同源異型盒基因HOXA13抗體
xy-10325R    Phospho-HDAC4 (Ser246)磷酸化組蛋白去乙?；?(Ser246)抗體
xy-10327R    Phospho-HDAC7(Ser155)磷酸化組蛋白去乙?；?抗體
xy-10328R    phospho-HDAC4 (Ser632)磷酸化組蛋白去乙酰化酶4抗體
xy-10330R    phospho-HDAC7(Ser486)磷酸化組蛋白去乙?；?抗體
xy-12269R    HIRIP3HIRA相互作用蛋白3抗體
xy-12287R    HOOK1HOOK1蛋白抗體
xy-10481R    HIV2 gp41 + gp160人類免疫缺陷病毒2型/2型艾滋病病毒gp41+gp160抗體
xy-10482R    HIV2 gp120 + gp160人類免疫缺陷病毒2型/2型艾滋病病毒gp41+gp160抗體
xy-13610R    HCG3HCG3蛋白抗體
xy-10226R    ErbB4HER4抗體
xy-3576R    DTSF肝素結合性表皮生長因子抗體
xy-9836R    HLC8肺癌相關蛋白8抗體
xy-4856R    Hepatitis C Virus NS5a丙型肝炎病毒NS5A抗體
xy-2560R    Histone H2A.x組蛋白H2AX抗體
xy-13597R    HESX1同源結構域轉錄因子HESX1抗體
xy-13598R    HESX1同源結構域轉錄因子HESX1抗體
xy-13599R    HoxC13同源盒蛋白HOX13抗體
xy-13600R    HOXD8同源盒轉錄因子8抗體