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酪氨酸酶相關(guān)蛋白1抗體

英文名稱 TRPC1
中文名稱 酪氨酸酶相關(guān)蛋白1抗體
別    名 TRPC1_HUMAN; Short transient receptor potential channel 1; TrpC1; Transient receptor protein 1; TRP-1; TRP 1; TRP 1 protein; TRP1; TRP1 protein; . HTRP 1; HTRP1; MGC133334; MGC133335; Mtrp1; Transient receptor potential cation channel subfamily C member 1; Transient receptor potential channel 1; Trp related protein 1; TRPC1; Trpc1 transient receptor potential cation channel subfamily C member 1.

說(shuō) 明 書(shū)
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  激酶和磷酸酶  合成與降解  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 87kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

Function:
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

Subunit:
Interacts with TRPC4AP (By similarity). Homotetramer and heterotetramer with TRPC4 and/or TRPC5. Interacts with TRPC3, TRPC4 and TRPC5. Interacts with ITPR3. Interacts with MX1 and RNF24. Interacts with FKBP4.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Seems to be ubiquitous.xy-9913R    HGFA肝細(xì)胞生長(zhǎng)因子激活蛋白抗體
xy-6537R    HDGF肝癌衍生生長(zhǎng)因子抗體（高遷移率族蛋白1樣蛋白2抗體）
xy-5386R    Phospho-Histone H3(Thr3)磷酸化組蛋白H3抗體
xy-9026R    HPRT次黃嘌呤磷酸核糖基轉(zhuǎn)移酶1抗體
xy-3776R    Histone H3 (acetyl K9)乙?；M蛋白H3抗體
xy-3748R    Acetyl and phospho-Histone H3 (Ac-K9/p-Ser10)乙?；土姿峄M蛋白H3抗體
xy-3779R    Histone H2A組蛋白H2A抗體
xy-3781R    Acetyl-Histone H2A(K5)乙?；M蛋白H2A抗體
xy-3782R    Acetyl-Histone H2B(K5)乙酰化組蛋白H2B抗體
xy-3783R    Acetyl-Histone H2B(K20)乙?；M蛋白H2B抗體
xy-5360R    Phospho-Histone H2A.X (Tyr143)磷酸化組蛋白H2AX抗體
xy-5361R    Phospho-HSP27 (Ser254)磷酸化熱休克蛋白27抗體
xy-5362R    phospho-HSP70(Tyr41)磷酸化熱休克蛋白70抗體
xy-5363R    phospho-HSF1(Ser303)磷酸化熱休克因子1抗體
xy-5364R    phospho-HSF1(Ser307)磷酸化熱休克因子1抗體
xy-5365R    phospho-HSP70 (Tyr525) 磷酸化熱休克蛋白70抗體
xy-6011R    HACE1E3泛素蛋白連接酶HACE1抗體
xy-3837R    Hamartin結(jié)節(jié)性硬化癥蛋白1抗體
xy-3828R    HNF4A肝細(xì)胞核因子4α抗體
xy-4001R    phospho-HNF4 (Ser313)磷酸化肝細(xì)胞核因子4α抗體
xy-6014R    HELLS淋巴特異性解旋酶抗體
xy-6013R    HRASLS2HRAS樣抑制因子2抗體
xy-6002R    HSP40 homolog熱休克蛋白家族40抗體
xy-6121R    RBMX糖蛋白P43抗體
xy-2366R    HSD3B7滋養(yǎng)層細(xì)胞抗原3β7抗體
xy-3672R    HSP22熱休克蛋白-22抗體
xy-3606R    HRH4組織胺H4受體抗體
xy-3618R    HSD11B2羥基類固醇脫氫酶11β2抗體
xy-3635R    HRH3組織胺H3受體抗體
xy-3176R    phospho-Histone H1.4 (Thr146)磷酸化組蛋白H1抗體
xy-15439R    HEATR4HEATR4蛋白抗體
xy-15410R    HAPLN1 透明質(zhì)酸及粘蛋白1抗體
xy-12353R    HES7轉(zhuǎn)錄因子HES7抗體
xy-10194R    HIP55/DBNL宮頸黏液蛋白相關(guān)蛋白抗體