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組織型纖溶酶原激活劑抗體

英文名稱 TPA
中文名稱 組織型纖溶酶原激活劑抗體
別    名 TPA Tissue Plasminogen Activator; Plasminogen activator tissue; Plasminogen activator tissue type; Plasminogen Activator Tissue Type Isoform 1 Preproprotein; PLAT; Reteplase; t PA; t-PA; tPA; T Plasminogen Activator; Tissue plasminogen activator (t PA); PATISS; Tissue type plasminogen activator; TPA; TPA1; AU020998; AW212668; D8Ertd2e; MGC18508; TPA_HUMAN; Tissue-type plasminogen activator; t-plasminogen activator; Alteplase; Tissue-type plasminogen activator chain B.
 
說 明 書 0.1ml  0.2ml  
研究領域 心血管  免疫學  神經(jīng)生物學  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
細胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Tissue-type plasminogen activator chain B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Function:
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.xy-10322R    H3N8 hemagglutinin流感病毒H3N8血凝素抗體
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xy-12309R    Hoxb3同源盒蛋白HoxB3抗體
xy-12335R    HFE遺傳性血色病蛋白相關蛋白1抗體
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xy-12316R    HHIPHHIP蛋白抗體
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xy-15459R    HERC1 鳥苷酸釋放因子p532蛋白抗體
xy-15460R    HERC2HERC2 E3泛素蛋白連接酶抗體
xy-15461R    HERC3HERC3 E3泛素蛋白連接酶抗體
xy-15462R    HERC4HERC4 E3泛素蛋白連接酶抗體
xy-15463R    HERC6HERC6 E3泛素蛋白連接酶抗體
xy-15464R    HERPUD1MMF誘導片段蛋白1抗體
xy-15465R    HERPUD2HERPUD蛋白家族成員2抗體
xy-15472R    HGD尿黑酸氧化酶抗體
xy-15473R    HGS 肝細胞生長調(diào)節(jié)因子酪氨酸激酶底物抗體
xy-15474R    HHATT細胞2識別黑色素瘤抗原抗體
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xy-15482R    hHR23b紫外切除修復蛋白RAD23B抗體
xy-15483R    HIBADH3-羥基異丁酸脫氫酶抗體
xy-15484R    HIBCH Hib乙酰輔酶A水解酶抗體
xy-15485R    HIC1腫瘤異常甲基化蛋白1抗體
xy-15486R    HIC2 腫瘤異常甲基化蛋白2抗體
xy-15487R    HIF Prolyl Hydroxylases缺氧誘導因子脯氨酰羥化酶4抗體
xy-15466R    HERV-FRD 人內(nèi)源性逆轉(zhuǎn)錄病毒膜糖蛋白2抗體
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xy-15451R    Hepatitis C virus NS5B丙型肝炎病毒NS5B抗體
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