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甲狀腺過氧化物酶抗體

英文名稱 Thyroid peroxidase
中文名稱 甲狀腺過氧化物酶抗體
別    名 MSA; PERT_HUMAN; TDH2A; Thyroid microsomal antigen; Thyroid peroxidase; Thyroperoxidase; TPO; TPX.

說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  生長因子和激素  激酶和磷酸酶  內(nèi)分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 101kDa
細(xì)胞定位 細(xì)胞膜 細(xì)胞外基質(zhì) 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Thyroid peroxidase
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011].

Function:
Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4).

Subunit:
Interacts with DUOX1, DUOX2 and CYBA.xy-3404R    Phospho-INPPL1(Tyr986 + Tyr987)磷酸化肌醇聚磷酸鹽磷酸酶樣蛋白1抗體
xy-1826R    Inhibin Beta C抑制素βC抗體
xy-1830R    IL-16白介素16抗體
xy-1825R    Inhibin beta B抑制素βB/Inhibin β B抗體
xy-1827R    IL-11白介素11抗體
xy-2624R    IL-22R白介素22受體抗體
xy-2626R    IL-26/AK155白介素26抗體
xy-2612R    IL-17D/IL-27白介素-17D抗體
xy-15531R    IBRDC1環(huán)指蛋白217抗體
xy-0605R    IL-2白介素2抗體(人)
xy-1460R    IL-23R白介素-23受體抗體
xy-1434R    IGFBP3胰島素樣生長因子結(jié)合蛋白3抗體
xy-1459R    IL-6R Beta/CD130/gp130白細(xì)胞介素6受體β抗體IL-6Rβ
xy-1463R    IFNGR1干擾素-gamma受體1抗體
xy-10540R    IL-1 Alpha Propeptide白介素1α前肽/IL-1α前肽抗體
xy-13771R    ITGA11整合素α11抗體
xy-15571R    IGFL2胰島素生長因子樣家族成員2抗體
xy-15540R    IDI2異戊烯基焦磷酸異構(gòu)酶2抗體
xy-2784R    ITKIL-2誘導(dǎo)型T細(xì)胞激酶抗體
xy-15568R    IGF2ASIGF2基因的互補基因1蛋白抗體
xy-15551R    IFI44L干擾素誘導(dǎo)蛋白44樣蛋白抗體
xy-10028R    ITGB4整合素β4抗體
xy-15575R    IGKV A18kappa輕鏈可變區(qū)抗體
xy-2583R    ICOS/CD278誘導(dǎo)協(xié)同刺激分子CD278抗體
xy-2630R    IL-31白細(xì)胞介素31抗體
xy-2627R    IL-28A/IFNL2白細(xì)胞介素28A抗體
xy-2632R    IL-32/NK4白介素32抗體
xy-2633R    IL-33/NFHEV白介素33抗體
xy-2634R    ILT2/CD85j細(xì)胞表面免疫球蛋白樣轉(zhuǎn)錄因子2抗體
xy-2635R    Integrin alpha 2/CD49b整合素α2抗體
xy-2636R    Integrin alpha 2b/CD41血小板膜糖蛋白ⅡbⅢa抗體
xy-2607R    IL-17RC/IL-17RL白介素17受體C抗體
xy-2584R    IGSF8免疫球蛋超家族成員8抗體