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小泛素樣修飾蛋白4抗體

英文名稱 SUMO4
中文名稱 小泛素樣修飾蛋白4抗體
別    名 dJ281H8.4; IDDM5; Small ubiquitin like modifier 4 protein; Small ubiquitin-like protein 4; Small ubiquitin-related modifier 4; SMT3 suppressor of mif two 3 homolog 2; SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae); SMT3H4; SUMO 4; SUMO-4; SUMO4; SUMO4_HUMAN.
  
說 明 書 0.2ml  
研究領域 細胞生物  轉錄調(diào)節(jié)因子  表觀遺傳學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, 
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 11kDa
細胞定位 細胞漿 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SUMO4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq, Jul 2008]

Function:
Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I.xy-11027R    KIF5A/NKHC1驅(qū)動蛋白KIF5A抗體
xy-8517R    KCC2神經(jīng)細胞鉀氯離子轉運蛋白抗體
xy-1033R    KRAS原癌基因K-ras抗體
xy-0749R    Kisspeptin腫瘤轉移抑制基因抗體
xy-0225R    KLH血藍蛋白抗體
xy-9857R    KCNG2心臟鉀離子通道蛋白亞基2抗體
xy-8358R    KLHDC8AKLHDC8A蛋白抗體
xy-4894R    Keratan Sulfate硫酸角質(zhì)素抗體
xy-1577R    KLF13腸道內(nèi)富含的Kruppel樣因子13
xy-9382R    ZFP103鋅指蛋白103抗體
xy-0734R    KGF纖維母細胞生長因子7抗體
xy-2772R    KLF2肺Kruppel樣因子抗體
xy-5869R    KLK5激肽釋放酶5抗體
xy-5866R    KLK13激肽釋放酶13抗體
xy-5867R    KLK15激肽釋放酶15抗體
xy-5868R    KLK2激肽釋放酶2抗體
xy-5865R    KLK12激肽釋放酶12抗體
xy-2501R    KiSS1 receptorG蛋白偶聯(lián)受體54抗體
xy-3527R    KIF17驅(qū)動蛋白家族KIF17抗體
xy-3644R    KLF9轉錄因子KLF9抗體
xy-2531R    NES/KLK10上皮細胞特異性蛋白1抗體
xy-5403R    phospho-KCNC1(Ser503)磷酸化離子通道蛋白Kv3.1抗體
xy-2812R    KAT4細胞周期基因1蛋白抗體
xy-2385R    KLF5驅(qū)動蛋白KIF5B抗體
xy-7752R    KLHL13kelch樣蛋白13抗體
xy-11569R    KCNN3鈣激活鉀通道蛋白3抗體
xy-11570R    KIBRA腎臟和腦蛋白抗體
xy-7751R    KIF2B有絲分裂驅(qū)動蛋白樣2B抗體
xy-7753R    KLHL9kelch樣蛋白9抗體
xy-7804R    KIF15驅(qū)動蛋白家族成員15抗體
xy-7808R    KNTC1著絲點關聯(lián)蛋白1抗體
xy-7806R    KLHDC5kelch樣蛋白5抗體
xy-7805R    KIFC1驅(qū)動蛋白家族成員C1抗體
xy-7807R    KLHL22Kelch樣蛋白22抗體
xy-6671R    KCND1電壓門控鉀通道Kv4.1抗體
xy-6674R    KCNK3酸敏感鉀離子通道蛋白3抗體