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鋅指蛋白279抗體

英文名稱 SUHW2/ZNF279
中文名稱 鋅指蛋白279抗體
別    名 5''OY11.1; D87009.C22.3; SUHW2; Suppressor of hairy wing homolog 2; Z280B_HUMAN; Zinc finger protein 279; Zinc finger protein 280B; Zinc finger protein 632; ZNF279; ZNF280B; ZNF632.
    
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Dog, Pig, Cow, Rabbit, Sheep, Cat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SUHW2/ZNF279
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]

Function:
May function as a transcription factor.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 4 C2H2-type zinc fingers.

Database links:xy-13654R    MAP4K5絲裂原活化蛋白激酶MAP4K5抗體
xy-13655R    MKLN1MKLN1抗體
xy-13688R    MAP2K1IP1絲裂原活化蛋白激酶相互作用蛋白1抗體
xy-13689R    MPP2MPP2蛋白抗體
xy-13690R    MS4A14睪丸發(fā)育相關(guān)蛋白抗體
xy-13691R    MS4A15MS4A15蛋白抗體
xy-13692R    MS4A6A四度跨膜蛋白3抗體
xy-6818R    MAGEA12黑色素瘤相關(guān)抗原12抗體
xy-6819R    MAGEA2黑色素瘤相關(guān)抗原2抗體
xy-6820R    MAGEA5黑色素瘤相關(guān)抗原5抗體
xy-10158R    Msx2同源盒基因Msx2抗體
xy-5470R    Phospho-MDM2(Thr218)磷酸化雙微體2癌基因抗體
xy-5471R    Phospho-MDM2(Ser186)磷酸化雙微體2癌基因抗體
xym-2182M    Melamine(1B12)三聚氰胺單克隆抗體
xy-6821R    MAGEB1黑色素瘤相關(guān)抗原B1抗體
xy-2721R    MCM5微小染色體維持缺陷蛋白5抗體
xy-4293R    MACC1結(jié)腸癌轉(zhuǎn)移相關(guān)蛋白1抗體
xy-4597R    MMP-1基質(zhì)金屬蛋白酶-1抗體
xy-5483R    phospho-MEF2C(Thr300)磷酸化肌細(xì)胞增強(qiáng)因子2C抗體
xy-5485R    Phospho-MEF2A(Thr319)磷酸化肌細(xì)胞增強(qiáng)因子2抗體
xy-5474R    phospho-MBP(Thr232)磷酸化髓鞘堿性蛋白抗體
xy-5475R    phospho-MBP(Tyr203)磷酸化髓鞘堿性蛋白抗體
xy-5478R    phospho-MYL6(Tyr29+Ser30)磷酸化肌球蛋白輕鏈6抗體
xy-5476R    phospho-P38 MAPK (Thr180)磷酸化p38MAPK抗體
xy-5477R    phospho-p38 MAPK (Tyr323)磷酸化p38MAPK抗體
xy-5480R    phospho-MEF2C(Ser396)磷酸化肌細(xì)胞增強(qiáng)因子2C抗體
xy-5487R    phospho-MAPK8 ( Thr183 + Tyr185)磷酸化氨基末端激酶2抗體
xy-12201R    MELK蛋白激酶MPK38抗體
xy-12206R    MGST1微粒體谷胱甘肽S轉(zhuǎn)移酶1抗體
xy-10074R    MUC13粘蛋白13抗體
xy-8689R    MEPE細(xì)胞外基質(zhì)磷酸化抗體
xy-2725R    Mast Cell Tryptase肥大細(xì)胞蛋白酶7抗體
xy-4128R    MAP4微管相關(guān)蛋白4抗體
xy-5120R    MSS126S蛋白酶調(diào)節(jié)亞型7抗體
xy-3629R    MEG1蛋白酪氨酸磷酸酶非受體型4抗體
xy-13355R    MBOAT4腦腸肽O?；D(zhuǎn)移酶抗體