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當前位置:上海信裕生物科技有限公司>>抗體>>一抗>> 酪氨酸激酶A/B/C抗體
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品 牌Abcam
廠商性質(zhì)生產(chǎn)商
所 在 地上海
更新時間:2015-06-10 12:47:30瀏覽次數(shù):294次
聯(lián)系我時,請告知來自 化工儀器網(wǎng)酪氨酸激酶A/B/C抗體
英文名稱 Trk A + B + C
中文名稱 酪氨酸激酶A/B/C抗體
別 名 TrkA/B/C; TrkA+B+C; Trk A; Trk B; Trk C; TrkB; TrkC; Tyrosine Receptor Kinase A; Tyrosine Receptor Kinase B; Tyrosine Receptor Kinase C.
說 明 書 0.1ml 0.2ml
研究領(lǐng)域 細胞生物 免疫學 神經(jīng)生物學 信號轉(zhuǎn)導 細胞凋亡
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken,
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 90kDa
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Trk A
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
產(chǎn)品介紹 background:
The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140),Trk B and Trk C. The prototype member of this gene family, Trk A, encodes a 140 kDa cell surface receptor, gp140, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia. By comparison, BDNF and to a lesser extent, NT-3, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145. The third member of the Trk receptor family, Trk C incodes a 140 kDa protein, Trk C gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3.An additional component of the Trk receptor complex, NGFR p175, binds to neurotrophic factors with low affinity but is required for efficient signaling. NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex.xy-5788R MMP20基質(zhì)金屬蛋白酶20
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